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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating lactate dehydrogenase level
Debug Stats
  • ### Total Build Time: 50 ms 28.492 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 426 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 443 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 189 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 1.052 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=14 ms Completed: 14 ms rowSize= 4.326 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 20.742 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.187 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased circulating lactate dehydrogenase level MP:0011971
Definition (1)
elevated blood level of the tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of lactate and pyruvate; measurements of circulating levels are used clinically as a diagnostic indicator of tissue breakdown, some forms of cancer or particular infection types
Synonyms (1)
"increased circulating LDH level" EXACT
Parents (2)
img abnormal circulating lactate dehydrogenase level MP:0011970
img increased lactate dehydrogenase level MP:0002944
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating lactate dehydrogenase level MP:0011970
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating lactate dehydrogenase level MP:0011970
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img increased lactate dehydrogenase level MP:0002944
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanSLC5A10125206solute carrier family 5 (sodium/sugar cotransporter), member 10
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1861441
img Jax MP, Pubmed Id: 21840300, MOUSE PHENOTYPE ID: MGI:1917605
img Jax MP, Pubmed Id: 23451068, MOUSE PHENOTYPE ID: MGI:1926089
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:97551
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1921982
HumanGPRC5C55890G protein-coupled receptor, family C, group 5, member C
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:97551
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1861441
img Jax MP, Pubmed Id: 21840300, MOUSE PHENOTYPE ID: MGI:1917605
img Jax MP, Pubmed Id: 23451068, MOUSE PHENOTYPE ID: MGI:1926089
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1921982
HumanSTX118676syntaxin 11
img Jax MP, Pubmed Id: 23451068, MOUSE PHENOTYPE ID: MGI:1926089
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:97551
img Jax MP, Pubmed Id: 21840300, MOUSE PHENOTYPE ID: MGI:1917605
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1861441
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1921982
HumanRAB27A5873RAB27A, member RAS oncogene family
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:97551
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1921982
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1861441
img Jax MP, Pubmed Id: 23451068, MOUSE PHENOTYPE ID: MGI:1926089
img Jax MP, Pubmed Id: 21840300, MOUSE PHENOTYPE ID: MGI:1917605
HumanPRF15551perforin 1 (pore forming protein)
img Jax MP, Pubmed Id: 23451068, MOUSE PHENOTYPE ID: MGI:1926089
img Jax MP, Pubmed Id: 21840300, MOUSE PHENOTYPE ID: MGI:1917605
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:97551
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1921982
img Jax MP, Pubmed Id: 23160464, MOUSE PHENOTYPE ID: MGI:1861441
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011971increased circulating lactate dehydrogenase level0self