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Details
Link-It Detail - Jax Mouse Phenotype - abnormal podocyte adhesion
Debug Stats
  • ### Total Build Time: 12 ms 8.442 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 500 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.018 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 574 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 2.908 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=2 ms Completed: 2 ms rowSize= 1.604 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal podocyte adhesion MP:0011864
Definition (1)
any anomaly in the adhesive properties of glomerular podocytes, resulting in abnormal cell to cell and cell to extracellular matrix (ECM) interactions; podocytes adhere tightly to ECM components of the glomerular basement membrane via an integrin-laminin-actin axis to maintain a functional filtration barrier in the presence of mechanical stress
Synonyms (1)
"abnormal podocyte-ECM adhesion" EXACT
Parents (2)
img abnormal cell adhesion MP:0003566
img abnormal podocyte physiology MP:0011863
Children (1)
img detached podocyte MP:0011869
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal cell adhesion MP:0003566
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053676img abnormal podocyte physiology MP:0011863
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanACTN481actinin, alpha 4
img Jax MP, Pubmed Id: 17082197, MOUSE PHENOTYPE ID: MGI:1890773
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011864abnormal podocyte adhesion0self