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Details
Link-It Detail - Jax Mouse Phenotype - abnormal kidney collecting duct intercalated cell morphology
Debug Stats
  • ### Total Build Time: 19 ms 7.404 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 448 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 669 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 608 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.099 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 1.604 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=2 ms Completed: 2 ms rowSize= 1.675 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.197 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal kidney collecting duct intercalated cell morphology MP:0011754
Definition (1)
any structural anomaly of any of the functionally distinct subtypes of cells (alpha or beta) found on the kidney collecting duct epithelium that regulate acid-base homeostasis and play an important role in the kidney's response to acidosis and alkalosis; alpha-intercalated cells secrete acid whereas beta-intercalated cells secrete base; metabolic acidosis results in the conversion of beta- cells to alpha-intercalated cells giving the kidney a greater ability to secrete protons and return pH to the normal range
Parents (1)
img abnormal kidney collecting duct epithelium morphology MP:0011843
Children (2)
img abnormal kidney collecting duct alpha-intercalated cell morphology MP:0011755
img abnormal kidney collecting duct beta-intercalated cell morphology MP:0011756
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053677img abnormal kidney collecting duct epithelium morphology MP:0011843
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanTFCP2L129842transcription factor CP2-like 1
img Jax MP, Pubmed Id: 17079272, MOUSE PHENOTYPE ID: MGI:2444691
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011754abnormal kidney collecting duct intercalated cell morphology0self