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Details
Link-It Detail - Jax Mouse Phenotype - glomerular crescent
Debug Stats
  • ### Total Build Time: 85 ms 16.170 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 366 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 696 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 591 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 1.588 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=55 ms Completed: 55 ms rowSize= 11.658 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
glomerular crescent MP:0011506
Definition (1)
formation of a crescent-shaped (semi-lunar) glomerular lesion corresponding to extracapillary proliferation of Bowman's capsular epithelium and acquiring a fibroblast-like spindled morphology, possibly stimulated by release of fibrinogen from a ruptured glomerular basement membrane; epithelial crescents occur in aggressive forms of glomerulonephritis, may be accompanied by collagen and fibrin deposition and/or monocyte and macrophage proliferation, may protrude into Bowman's space, and ultimately compress and destroy the glomerular tuft
Parents (1)
img abnormal renal glomerulus morphology MP:0005325
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053678img abnormal renal glomerulus morphology MP:0005325
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanTNFRSF13B23495tumor necrosis factor receptor superfamily, member 13B
Click here to display 23 evidence detail records.
HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
Click here to display 23 evidence detail records.
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
Click here to display 23 evidence detail records.
HumanWT17490Wilms tumor 1
Click here to display 23 evidence detail records.
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
Click here to display 23 evidence detail records.
HumanPOU2AF15450POU class 2 associating factor 1
Click here to display 23 evidence detail records.
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Click here to display 23 evidence detail records.
HumanNFE2L24780nuclear factor, erythroid 2-like 2
Click here to display 23 evidence detail records.
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Click here to display 23 evidence detail records.
HumanILK3611integrin-linked kinase
Click here to display 23 evidence detail records.
HumanHMOX13162heme oxygenase (decycling) 1
Click here to display 23 evidence detail records.
HumanGAS62621growth arrest-specific 6
Click here to display 23 evidence detail records.
HumanCOL4A31285collagen, type IV, alpha 3 (Goodpasture antigen)
Click here to display 23 evidence detail records.
HumanCCR11230chemokine (C-C motif) receptor 1
Click here to display 23 evidence detail records.
HumanCD151977CD151 molecule (Raph blood group)
Click here to display 23 evidence detail records.
HumanCD1D912CD1d molecule
Click here to display 23 evidence detail records.
HumanC1QA712complement component 1, q subcomponent, A chain
Click here to display 23 evidence detail records.
HumanFASLG356Fas ligand (TNF superfamily, member 6)
Click here to display 23 evidence detail records.
HumanFAS355Fas cell surface death receptor
Click here to display 23 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011506glomerular crescent0self