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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to dopaminergic neuron neurotoxicity
Debug Stats
  • ### Total Build Time: 20 ms 15.460 KB
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  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 8.201 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.198 KB
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Jax Mouse Phenotype (1)
decreased susceptibility to dopaminergic neuron neurotoxicity MP:0011452
Definition (1)
less than normal amount of dopaminergic neuronal cell death following exposure to a neurotoxic compound, such as MPTP-induced cell death occurring through interference in mitochondrial metabolism
Synonyms (1)
"reduced susceptibility to dopaminergic neuron neurotoxicity" EXACT
Parents (1)
img decreased susceptibility to neuronal excitotoxicity MP:0008236
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053766img decreased susceptibility to neuronal excitotoxicity MP:0008236
img mammalian phenotype MP:0000001img cellular phenotype MP:00053849img decreased susceptibility to neuronal excitotoxicity MP:0008236
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036318img decreased susceptibility to neuronal excitotoxicity MP:0008236
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanFAF111124Fas (TNFRSF6) associated factor 1
Click here to display 19 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
Click here to display 19 evidence detail records.
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
Click here to display 19 evidence detail records.
HumanSPP16696secreted phosphoprotein 1
Click here to display 19 evidence detail records.
HumanSNCG6623synuclein, gamma (breast cancer-specific protein 1)
Click here to display 19 evidence detail records.
HumanSNCA6622synuclein, alpha (non A4 component of amyloid precursor)
Click here to display 19 evidence detail records.
HumanSLC6A36531solute carrier family 6 (neurotransmitter transporter), member 3
Click here to display 19 evidence detail records.
HumanMAPK105602mitogen-activated protein kinase 10
Click here to display 19 evidence detail records.
HumanMAPK95601mitogen-activated protein kinase 9
Click here to display 19 evidence detail records.
HumanPLA2G4A5321phospholipase A2, group IVA (cytosolic, calcium-dependent)
Click here to display 19 evidence detail records.
HumanMAOB4129monoamine oxidase B
Click here to display 19 evidence detail records.
HumanGPR372861G protein-coupled receptor 37 (endothelin receptor type B-like)
Click here to display 19 evidence detail records.
HumanPARP1142poly (ADP-ribose) polymerase 1
Click here to display 19 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011452decreased susceptibility to dopaminergic neuron neurotoxicity0self