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Details
Link-It Detail - Jax Mouse Phenotype - mesangial cell hyperplasia
Debug Stats
  • ### Total Build Time: 59 ms 21.530 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 589 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=54 ms Completed: 54 ms rowSize= 17.162 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
mesangial cell hyperplasia MP:0011427
Definition (1)
increased number of the phagocytic cells in the capillary tuft of the renal glomerulus, interposed between endothelial cells and the basement membrane in the central or stalk region of the tuft
Synonyms (1)
"mesangial hypercellularity" EXACT
Parents (1)
img abnormal mesangial cell morphology MP:0005327
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:000536710img abnormal mesangial cell morphology MP:0005327
Genes (28)

Species:
human : 28
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanKIRREL55243kin of IRRE like (Drosophila)
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HumanCD2AP23607CD2-associated protein
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HumanTNFRSF13B23495tumor necrosis factor receptor superfamily, member 13B
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HumanTRAF3IP210758TRAF3 interacting protein 2
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HumanMTA29219metastasis associated 1 family, member 2
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HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
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HumanWT17490Wilms tumor 1
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HumanWAS7454Wiskott-Aldrich syndrome
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HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
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HumanSYK6850spleen tyrosine kinase
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HumanPKN15585protein kinase N1
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HumanPKHD15314polycystic kidney and hepatic disease 1 (autosomal recessive)
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HumanNPHS14868nephrosis 1, congenital, Finnish type (nephrin)
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HumanNOS34846nitric oxide synthase 3 (endothelial cell)
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HumanNFE2L24780nuclear factor, erythroid 2-like 2
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HumanLCAT3931lecithin-cholesterol acyltransferase
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HumanIFNG3458interferon, gamma
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HumanHPRT13251hypoxanthine phosphoribosyltransferase 1
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HumanCFH3075complement factor H
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HumanGDNF2668glial cell derived neurotrophic factor
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HumanMARK22011MAP/microtubule affinity-regulating kinase 2
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HumanGADD45A1647growth arrest and DNA-damage-inducible, alpha
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HumanCOL4A51287collagen, type IV, alpha 5
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HumanCOL4A31285collagen, type IV, alpha 3 (Goodpasture antigen)
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HumanCEBPB1051CCAAT/enhancer binding protein (C/EBP), beta
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XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011427mesangial cell hyperplasia0self