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Details
Link-It Detail - Jax Mouse Phenotype - abnormal kidney interstitium morphology
Debug Stats
  • ### Total Build Time: 21 ms 32.725 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 650 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 196 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 581 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.038 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.578 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 26.997 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal kidney interstitium morphology MP:0011425
Definition (1)
any structural anomaly of the kidney region located between the nephrons, ureteric epithelia (ureteric tips, trunk and collecting duct system) and renal vasculature, and composed of renal support cells, including fibroblasts and macrophages, and mesenchymal stroma or interstitial cells; the renal vasculature lies within the renal interstitium but is not a part of it; various conditions can lead to scarring (fibrosis) and congestion of this area, which can cause kidney dysfunction and failure
Synonyms (1)
"abnormal renal interstitium morphology" EXACT
Parents (1)
img abnormal kidney morphology MP:0002135
Children (2)
img abnormal perihilar interstitium morphology MP:0011337
img renal interstitial fibrosis MP:0003215
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053675img abnormal kidney morphology MP:0002135
Genes (47)

Species:
human : 47
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanKCP375616kielin/chordin-like protein
INFERRED
HumanGLIS284662GLIS family zinc finger 2
INFERRED
HumanPDSS257107prenyl (decaprenyl) diphosphate synthase, subunit 2
INFERRED
HumanSLC2A956606solute carrier family 2 (facilitated glucose transporter), member 9
INFERRED
HumanTRPV556302transient receptor potential cation channel, subfamily V, member 5
INFERRED
HumanLIN7C55327lin-7 homolog C (C. elegans)
INFERRED
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
INFERRED
HumanINVS27130inversin
img Jax MP, Pubmed Id: 8402909, MOUSE PHENOTYPE ID: MGI:88138
img Jax MP, Pubmed Id: 22912827, MOUSE PHENOTYPE ID: MGI:894695
img Jax MP, Pubmed Id: 19820125, MOUSE PHENOTYPE ID: MGI:1927616
img Jax MP, Pubmed Id: 11292619, MOUSE PHENOTYPE ID: MGI:87964
img Jax MP, Pubmed Id: 21292981, MOUSE PHENOTYPE ID: MGI:1330838
img Jax MP, Pubmed Id: 15213262, MOUSE PHENOTYPE ID: MGI:1335082
HumanNPHP327031nephronophthisis 3 (adolescent)
INFERRED
HumanWWTR125937WW domain containing transcription regulator 1
INFERRED
HumanKIF3A11127kinesin family member 3A
INFERRED
HumanGRHPR9380glyoxylate reductase/hydroxypyruvate reductase
INFERRED
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
INFERRED
HumanXDH7498xanthine dehydrogenase
INFERRED
HumanWT17490Wilms tumor 1
INFERRED
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
INFERRED
HumanTRPS17227trichorhinophalangeal syndrome I
img Jax MP, Pubmed Id: 15213262, MOUSE PHENOTYPE ID: MGI:1335082
img Jax MP, Pubmed Id: 11292619, MOUSE PHENOTYPE ID: MGI:87964
img Jax MP, Pubmed Id: 8402909, MOUSE PHENOTYPE ID: MGI:88138
img Jax MP, Pubmed Id: 22912827, MOUSE PHENOTYPE ID: MGI:894695
img Jax MP, Pubmed Id: 19820125, MOUSE PHENOTYPE ID: MGI:1927616
img Jax MP, Pubmed Id: 21292981, MOUSE PHENOTYPE ID: MGI:1330838
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED
HumanREN5972renin
INFERRED
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED
HumanLGMN5641legumain
img Jax MP, Pubmed Id: 8402909, MOUSE PHENOTYPE ID: MGI:88138
img Jax MP, Pubmed Id: 15213262, MOUSE PHENOTYPE ID: MGI:1335082
img Jax MP, Pubmed Id: 22912827, MOUSE PHENOTYPE ID: MGI:894695
img Jax MP, Pubmed Id: 11292619, MOUSE PHENOTYPE ID: MGI:87964
img Jax MP, Pubmed Id: 19820125, MOUSE PHENOTYPE ID: MGI:1927616
img Jax MP, Pubmed Id: 21292981, MOUSE PHENOTYPE ID: MGI:1330838
HumanPPP3R15534protein phosphatase 3, regulatory subunit B, alpha
INFERRED
HumanPKHD15314polycystic kidney and hepatic disease 1 (autosomal recessive)
INFERRED
HumanPKD15310polycystic kidney disease 1 (autosomal dominant)
INFERRED
HumanMYO1E4643myosin IE
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011425abnormal kidney interstitium morphology0self