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Details
Link-It Detail - Jax Mouse Phenotype - impaired adaptive thermogenesis
Debug Stats
  • ### Total Build Time: 123 ms 21.696 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 390 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 343 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 192 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=32 ms Completed: 32 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 586 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.585 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=80 ms Completed: 80 ms rowSize= 17.314 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.169 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
impaired adaptive thermogenesis MP:0011049
Definition (1)
inability or reduced ability to produce heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death
Synonyms (1)
"impaired adaptive thermoregulation" EXACT
Parents (1)
img abnormal adaptive thermogenesis MP:0011019
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img abnormal adaptive thermogenesis MP:0011019
Genes (40)

Species:
human : 40
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanPPARGC1B133522peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Click here to display 63 evidence detail records.
HumanTPH2121278tryptophan hydroxylase 2
Click here to display 63 evidence detail records.
HumanACSS184532acyl-CoA synthetase short-chain family member 1
Click here to display 63 evidence detail records.
HumanCIDEC63924cell death-inducing DFFA-like effector c
Click here to display 63 evidence detail records.
HumanPNPLA257104patatin-like phospholipase domain containing 2
Click here to display 63 evidence detail records.
HumanKDM3A55818lysine (K)-specific demethylase 3A
Click here to display 63 evidence detail records.
HumanPNPLA850640patatin-like phospholipase domain containing 8
Click here to display 63 evidence detail records.
HumanATE111101arginyltransferase 1
Click here to display 63 evidence detail records.
HumanPPARGC1A10891peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Click here to display 63 evidence detail records.
HumanNMU10874neuromedin U
Click here to display 63 evidence detail records.
HumanKCNAB28514potassium voltage-gated channel, shaker-related subfamily, beta member 2
Click here to display 63 evidence detail records.
HumanNCOA38202nuclear receptor coactivator 3
Click here to display 63 evidence detail records.
HumanUCP17350uncoupling protein 1 (mitochondrial, proton carrier)
Click here to display 63 evidence detail records.
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
Click here to display 63 evidence detail records.
HumanTNFAIP37128tumor necrosis factor, alpha-induced protein 3
Click here to display 63 evidence detail records.
HumanTHRA7067thyroid hormone receptor, alpha
Click here to display 63 evidence detail records.
HumanSTAT5B6777signal transducer and activator of transcription 5B
Click here to display 63 evidence detail records.
HumanSTAT5A6776signal transducer and activator of transcription 5A
Click here to display 63 evidence detail records.
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
Click here to display 63 evidence detail records.
HumanSLC2A26514solute carrier family 2 (facilitated glucose transporter), member 2
Click here to display 63 evidence detail records.
HumanPPARA5465peroxisome proliferator-activated receptor alpha
Click here to display 63 evidence detail records.
HumanPLIN15346perilipin 1
Click here to display 63 evidence detail records.
HumanMC5R4161melanocortin 5 receptor
Click here to display 63 evidence detail records.
HumanLEPR3953leptin receptor
Click here to display 63 evidence detail records.
HumanLEP3952leptin
Click here to display 63 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011049impaired adaptive thermogenesis0self