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Details
Link-It Detail - Jax Mouse Phenotype - decreased activation-induced cell death of T cells
Debug Stats
  • ### Total Build Time: 70 ms 13.334 KB
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Jax Mouse Phenotype (1)
decreased activation-induced cell death of T cells MP:0010677
Definition (1)
decreased frequency of the type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors
Synonyms (1)
"decreased antigen-driven apoptosis" BROAD
Parents (2)
img decreased apoptosis MP:0006043
img abnormal activation-induced cell death of T cells MP:0010670
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img decreased apoptosis MP:0006043
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal activation-induced cell death of T cells MP:0010670
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal activation-induced cell death of T cells MP:0010670
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal activation-induced cell death of T cells MP:0010670
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanHAVCR284868hepatitis A virus cellular receptor 2
img Jax MP, Pubmed Id: 22875804, MOUSE PHENOTYPE ID: MGI:2159682
img Jax MP, Pubmed Id: 11342603, MOUSE PHENOTYPE ID: MGI:88338
HumanCD44960CD44 molecule (Indian blood group)
img Jax MP, Pubmed Id: 22875804, MOUSE PHENOTYPE ID: MGI:2159682
img Jax MP, Pubmed Id: 11342603, MOUSE PHENOTYPE ID: MGI:88338
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010677decreased activation-induced cell death of T cells0self