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Details
Link-It Detail - Jax Mouse Phenotype - decreased activation-induced B cell apoptosis
Debug Stats
  • ### Total Build Time: 56 ms 18.536 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 418 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
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  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 8.201 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased activation-induced B cell apoptosis MP:0010675
Definition (1)
decreased frequency of B cell apoptosis that occurs upon engagement of either the B cell receptor or CD40, but not both; the engagement leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death
Synonyms (1)
"reduced activation-induced cell death of B cells" EXACT
Parents (2)
img decreased apoptosis MP:0006043
img abnormal activation-induced B cell apoptosis MP:0010669
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img decreased apoptosis MP:0006043
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal activation-induced B cell apoptosis MP:0010669
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanSPPL2A84888signal peptide peptidase like 2A
img Jax MP, Pubmed Id: 23334419, MOUSE PHENOTYPE ID: MGI:2654703
img Jax MP, Pubmed Id: 23267013, MOUSE PHENOTYPE ID: MGI:1913802
img Jax MP, Pubmed Id: 23223530, MOUSE PHENOTYPE ID: MGI:108022
HumanOTUD7B56957OTU domain containing 7B
img Jax MP, Pubmed Id: 23267013, MOUSE PHENOTYPE ID: MGI:1913802
img Jax MP, Pubmed Id: 23334419, MOUSE PHENOTYPE ID: MGI:2654703
img Jax MP, Pubmed Id: 23223530, MOUSE PHENOTYPE ID: MGI:108022
HumanPKN15585protein kinase N1
img Jax MP, Pubmed Id: 23223530, MOUSE PHENOTYPE ID: MGI:108022
img Jax MP, Pubmed Id: 23267013, MOUSE PHENOTYPE ID: MGI:1913802
img Jax MP, Pubmed Id: 23334419, MOUSE PHENOTYPE ID: MGI:2654703
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010675decreased activation-induced B cell apoptosis0self