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Details
Link-It Detail - Jax Mouse Phenotype - increased activation-induced B cell apoptosis
Debug Stats
  • ### Total Build Time: 37 ms 14.621 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 418 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
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  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 4.298 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased activation-induced B cell apoptosis MP:0010674
Definition (1)
increased frequency of B cell apoptosis that occurs upon engagement of either the B cell receptor or CD40, but not both; the engagement leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death
Synonyms (1)
"increased activated B cell apoptosis" EXACT
Parents (2)
img increased apoptosis MP:0006042
img abnormal activation-induced B cell apoptosis MP:0010669
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img increased apoptosis MP:0006042
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal activation-induced B cell apoptosis MP:0010669
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal activation-induced B cell apoptosis MP:0010669
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanNFKBIA4792nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 21333553, MOUSE PHENOTYPE ID: MGI:104741
HumanBCL6604B-cell CLL/lymphoma 6
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 21333553, MOUSE PHENOTYPE ID: MGI:104741
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010674increased activation-induced B cell apoptosis0self