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Details
Link-It Detail - Jax Mouse Phenotype - increased cardiovascular system tumor incidence
Debug Stats
  • [ From Cache ]
  • ### Total Build Time: 29 ms 26.072 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 422 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 282 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 598 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 2.362 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.578 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=28 ms Completed: 28 ms rowSize= 19.531 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.185 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased cardiovascular system tumor incidence MP:0010291
Definition (1)
greater than the expected number of tumors originating in the cardiovascular system in a given population in a given time period
Parents (1)
img increased organ/body region tumor incidence MP:0010274
Children (5)
img hemangiosarcoma MP:0003667
img atrial myxoma MP:0003392
img increased cardiac rhabdomyoma incidence MP:0006140
img hemangioma MP:0002947
img increased cardiac fibroma incidence MP:0010339
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020067img increased organ/body region tumor incidence MP:0010274
Genes (42)

Species:
human : 42
SpeciesGeneGeneIdGene NameEvidence
HumanATAD579915ATPase family, AAA domain containing 5
INFERRED
HumanRINT160561RAD50 interactor 1
INFERRED
HumanPINX154984PIN2/TERF1 interacting, telomerase inhibitor 1
INFERRED
HumanGNMT27232glycine N-methyltransferase
INFERRED
HumanFBXO426272F-box protein 4
INFERRED
HumanTUSC211334tumor suppressor candidate 2
INFERRED
HumanPDCD1011235programmed cell death 10
INFERRED
HumanIQGAP210788IQ motif containing GTPase activating protein 2
INFERRED
HumanHTATIP210553HIV-1 Tat interactive protein 2, 30kDa
INFERRED
HumanTNK18711tyrosine kinase, non-receptor, 1
INFERRED
HumanTP638626tumor protein p63
INFERRED
HumanMAD1L18379MAD1 mitotic arrest deficient-like 1 (yeast)
INFERRED
HumanPRDM27799PR domain containing 2, with ZNF domain
INFERRED
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
INFERRED
HumanTSC27249tuberous sclerosis 2
INFERRED
HumanTSC17248tuberous sclerosis 1
INFERRED
HumanTP737161tumor protein p73
INFERRED
HumanTP53BP27159tumor protein p53 binding protein, 2
INFERRED
HumanTP537157tumor protein p53
INFERRED
HumanTHBS17057thrombospondin 1
INFERRED
HumanSTK116794serine/threonine kinase 11
INFERRED
HumanRAG15896recombination activating gene 1
INFERRED
HumanPTEN5728phosphatase and tensin homolog
INFERRED
HumanPRKAR1A5573protein kinase, cAMP-dependent, regulatory, type I, alpha
INFERRED
HumanPMS25395PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
INFERRED
HumanPRDX15052peroxiredoxin 1
INFERRED
HumanOGG149688-oxoguanine DNA glycosylase
INFERRED
HumanNOTCH14851notch 1
INFERRED
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
INFERRED
HumanMET4233met proto-oncogene
INFERRED
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
INFERRED
HumanKRAS3845Kirsten rat sarcoma viral oncogene homolog
INFERRED
HumanIRF13659interferon regulatory factor 1
INFERRED
HumanHPRT13251hypoxanthine phosphoribosyltransferase 1
INFERRED
HumanFOXO32309forkhead box O3
INFERRED
HumanFOXO12308forkhead box O1
INFERRED
HumanE2F11869E2F transcription factor 1
INFERRED
HumanDCN1634decorin
INFERRED
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
INFERRED
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
INFERRED
HumanCDKN1A1026cyclin-dependent kinase inhibitor 1A (p21, Cip1)
INFERRED
HumanACTB60actin, beta
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010291increased cardiovascular system tumor incidence0self