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Details
Link-It Detail - Jax Mouse Phenotype - decreased T follicular helper cell number
Debug Stats
  • ### Total Build Time: 50 ms 45.318 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 418 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.043 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=21 ms Completed: 21 ms rowSize= 21.900 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 20.235 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased T follicular helper cell number MP:0010187
Definition (1)
reduced number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Parents (2)
img decreased CD4-positive T cell number MP:0008075
img abnormal T follicular helper cell number MP:0010185
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538714img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539715img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal T follicular helper cell number MP:0010185
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanBATF10538basic leucine zipper transcription factor, ATF-like
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23455674, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:1098211
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
img Jax MP, Pubmed Id: 23455674, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:1098211
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
HumanPIK3CD5293phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP, Pubmed Id: 23455674, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:1098211
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
HumanBCL6604B-cell CLL/lymphoma 6
img Jax MP, Pubmed Id: 21636294, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23455674, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:1098211
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010187decreased T follicular helper cell number0self