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Details
Link-It Detail - Jax Mouse Phenotype - increased T follicular helper cell number
Debug Stats
  • ### Total Build Time: 31 ms 40.591 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 418 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.043 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=7 ms Completed: 7 ms rowSize= 21.900 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 15.508 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased T follicular helper cell number MP:0010186
Definition (1)
greater number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Parents (2)
img increased CD4-positive T cell number MP:0008074
img abnormal T follicular helper cell number MP:0010185
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img increased CD4-positive T cell number MP:0008074
img mammalian phenotype MP:0000001img immune system phenotype MP:000538714img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539715img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal T follicular helper cell number MP:0010185
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal T follicular helper cell number MP:0010185
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanRC3H1149041ring finger and CCCH-type domains 1
img Jax MP, Pubmed Id: 21606507, MOUSE PHENOTYPE ID: MGI:1926194
img Jax MP
img Jax MP, Pubmed Id: 21857655, MOUSE PHENOTYPE ID: MGI:96398
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP, Pubmed Id: 22700722, MOUSE PHENOTYPE ID: MGI:2685397
HumanTNIP110318TNFAIP3 interacting protein 1
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP
img Jax MP, Pubmed Id: 22700722, MOUSE PHENOTYPE ID: MGI:2685397
img Jax MP, Pubmed Id: 21606507, MOUSE PHENOTYPE ID: MGI:1926194
img Jax MP, Pubmed Id: 21857655, MOUSE PHENOTYPE ID: MGI:96398
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
img Jax MP, Pubmed Id: 21857655, MOUSE PHENOTYPE ID: MGI:96398
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
img Jax MP, Pubmed Id: 22700722, MOUSE PHENOTYPE ID: MGI:2685397
img Jax MP, Pubmed Id: 21606507, MOUSE PHENOTYPE ID: MGI:1926194
img Jax MP
HumanID33399inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
img Jax MP, Pubmed Id: 21606507, MOUSE PHENOTYPE ID: MGI:1926194
img Jax MP
img Jax MP, Pubmed Id: 21857655, MOUSE PHENOTYPE ID: MGI:96398
img Jax MP, Pubmed Id: 22700722, MOUSE PHENOTYPE ID: MGI:2685397
img Jax MP, Pubmed Id: 20826752, MOUSE PHENOTYPE ID: MGI:104512
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010186increased T follicular helper cell number0self