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Details
Link-It Detail - Jax Mouse Phenotype - abnormal T follicular helper cell morphology
Debug Stats
  • ### Total Build Time: 13 ms 11.900 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 416 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 423 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 601 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 1.058 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.321 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 3.789 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.182 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal T follicular helper cell morphology MP:0010184
Definition (1)
any structural anomaly of a CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Parents (1)
img abnormal CD4-positive helper T cell morphology MP:0010183
Children (2)
img abnormal T follicular helper cell differentiation MP:0010188
img abnormal T follicular helper cell number MP:0010185
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive helper T cell morphology MP:0010183
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal CD4-positive helper T cell morphology MP:0010183
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal CD4-positive helper T cell morphology MP:0010183
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanRC3H1149041ring finger and CCCH-type domains 1
INFERRED
HumanBATF10538basic leucine zipper transcription factor, ATF-like
INFERRED
HumanTNIP110318TNFAIP3 interacting protein 1
INFERRED
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
INFERRED
HumanPIK3CD5293phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
INFERRED
HumanID33399inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INFERRED
HumanBCL6604B-cell CLL/lymphoma 6
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010184abnormal T follicular helper cell morphology0self