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Details
Link-It Detail - Jax Mouse Phenotype - leptocytosis
Debug Stats
  • ### Total Build Time: 17 ms 64.835 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 550 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 182 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 586 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.583 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 60.318 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
leptocytosis MP:0010175
Definition (1)
the presence of unusually thin or flattened red blood cells that when stained show a dark center and a peripheral ring of hemoglobin, separated by a pale unstained ring containing less hemoglobin, resulting in a bull's-eye appearance and resembling a 3D sombrero when viewed under EM; seen in certain anemias, thalassemias, hemoglobinopathies, obstructive jaundice, and the post-splenectomy state
Synonyms (1)
"Mexican hat erythrocytes" EXACT
Parents (1)
img abnormal erythrocyte morphology MP:0002447
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal erythrocyte morphology MP:0002447
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanTSPAN33340348tetraspanin 33
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
HumanSTEAP355240STEAP family member 3, metalloreductase
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
HumanSLC40A130061solute carrier family 40 (iron-regulated transporter), member 1
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
HumanPPP1R15A23645protein phosphatase 1, regulatory subunit 15A
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
HumanHBB3043hemoglobin, beta
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
HumanFECH2235ferrochelatase
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 17289807, MOUSE PHENOTYPE ID: MGI:1315204
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
img Jax MP, Pubmed Id: 15545996, MOUSE PHENOTYPE ID: MGI:2158492
img Jax MP, Pubmed Id: 16478986, MOUSE PHENOTYPE ID: MGI:1927072
img Jax MP, Pubmed Id: 8781443, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 430558, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 18955558, MOUSE PHENOTYPE ID: MGI:1915678
img Jax MP, Pubmed Id: 12920035, MOUSE PHENOTYPE ID: MGI:96014
img Jax MP, Pubmed Id: 17158226, MOUSE PHENOTYPE ID: MGI:1919012
img Jax MP, Pubmed Id: 1939658, MOUSE PHENOTYPE ID: MGI:95513
img Jax MP, Pubmed Id: 23040355, MOUSE PHENOTYPE ID: MGI:96021
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010175leptocytosis0self