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Details
Link-It Detail - Jax Mouse Phenotype - decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
Debug Stats
  • ### Total Build Time: 127 ms 49.759 KB
  • CONCEPT_NAME gt=19 ms Completed: 19 ms rowSize= 476 bytes
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  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 372 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 196 bytes
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  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1.079 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=64 ms Completed: 64 ms rowSize= 16.659 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=24 ms Completed: 24 ms rowSize= 29.638 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.211 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number MP:0010169
Definition (1)
a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release
Synonyms (1)
"reduced suppressor T lymphocyte number" BROAD
Parents (2)
img decreased CD4-positive T cell number MP:0008075
img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased CD4-positive T cell number MP:0008075
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanGMNN51053geminin, DNA replication inhibitor
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
HumanFOXP350943forkhead box P3
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
HumanBATF10538basic leucine zipper transcription factor, ATF-like
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
HumanSTAT5B6777signal transducer and activator of transcription 5B
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
HumanIL23558interleukin 2
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
HumanHLA-DQB13119
img Jax MP, Pubmed Id: 16493008, MOUSE PHENOTYPE ID: MGI:103035
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 16709807, MOUSE PHENOTYPE ID: MGI:96548
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 12612578, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20107189, MOUSE PHENOTYPE ID: MGI:1927344
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010169decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number0self