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Details
Link-It Detail - Jax Mouse Phenotype - impaired behavioral response to addictive substance
Debug Stats
  • ### Total Build Time: 103 ms 23.253 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 430 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=20 ms Completed: 20 ms rowSize= 1.979 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=11 ms Completed: 11 ms rowSize= 2.964 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=54 ms Completed: 54 ms rowSize= 15.115 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.188 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
impaired behavioral response to addictive substance MP:0009750
Definition (1)
decreased sensitivity to an addictive substance capable of inducing the appearance of behavioral response, such as induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response
Parents (2)
img abnormal behavioral response to addictive substance MP:0009748
img impaired behavioral response to xenobiotic MP:0009747
Children (4)
img impaired behavioral response to cocaine MP:0009758
img impaired behavioral response to morphine MP:0009757
img impaired behavioral response to alcohol MP:0009755
img impaired behavioral response to nicotine MP:0009756
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img behavior/neurological phenotype MP:00053866img abnormal behavioral response to addictive substance MP:0009748
img mammalian phenotype MP:0000001img behavior/neurological phenotype MP:00053866img impaired behavioral response to xenobiotic MP:0009747
Genes (40)

Species:
human : 40
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGRASP160622GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
INFERRED
HumanLRRK2120892leucine-rich repeat kinase 2
Click here to display 28 evidence detail records.
HumanPPP1R1B84152protein phosphatase 1, regulatory (inhibitor) subunit 1B
Click here to display 28 evidence detail records.
HumanHIPK228996homeodomain interacting protein kinase 2
Click here to display 28 evidence detail records.
HumanGPRASP19737G protein-coupled receptor associated sorting protein 1
INFERRED
HumanRPS6KA59252ribosomal protein S6 kinase, 90kDa, polypeptide 5
INFERRED
HumanWFS17466Wolfram syndrome 1 (wolframin)
Click here to display 28 evidence detail records.
HumanTRPV17442transient receptor potential cation channel, subfamily V, member 1
INFERRED
HumanTACR16869tachykinin receptor 1
Click here to display 28 evidence detail records.
HumanSLC18A26571solute carrier family 18 (vesicular monoamine transporter), member 2
INFERRED
HumanRGS45999regulator of G-protein signaling 4
INFERRED
HumanPRKCG5582protein kinase C, gamma
INFERRED
HumanPLAT5327plasminogen activator, tissue
INFERRED
HumanOPRM14988opioid receptor, mu 1
INFERRED
HumanOPRL14987opiate receptor-like 1
INFERRED
HumanOPRK14986opioid receptor, kappa 1
INFERRED
HumanOPRD14985opioid receptor, delta 1
INFERRED
HumanNPY1R4886neuropeptide Y receptor Y1
INFERRED
HumanHTR633625-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
INFERRED
HumanGRM52915glutamate receptor, metabotropic 5
INFERRED
HumanGNAZ2781guanine nucleotide binding protein (G protein), alpha z polypeptide
Click here to display 28 evidence detail records.
HumanSLC29A12030solute carrier family 29 (equilibrative nucleoside transporter), member 1
INFERRED
HumanDRD41815dopamine receptor D4
Click here to display 28 evidence detail records.
HumanDRD31814dopamine receptor D3
INFERRED
HumanDRD21813dopamine receptor D2
Click here to display 28 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009750impaired behavioral response to addictive substance0self