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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interstitial cell of Cajal morphology
Debug Stats
  • ### Total Build Time: 220 ms 9.391 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 420 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 537 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=207 ms Completed: 207 ms rowSize= 591 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 596 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.588 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 4.204 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.184 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal interstitial cell of Cajal morphology MP:0009536
Definition (1)
any structural anomaly in the type of cell found in the gastrointestinal tract and serving as a pacemaker that triggers gut contraction; ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumours (GISTs) arise; abnormalities in the ICC network can cause chronic intestinal pseudo-obstruction
Synonyms (1)
"abnormal ICC morphology" EXACT
Parents (1)
img abnormal digestive system morphology MP:0000462
Children (1)
img interstitial cells of Cajal hyperplasia MP:0009537
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img digestive/alimentary phenotype MP:00053814img abnormal digestive system morphology MP:0000462
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanLEP3952leptin
img Jax MP, Pubmed Id: 11438492, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 19917283, MOUSE PHENOTYPE ID: MGI:104663
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img Jax MP, Pubmed Id: 11438492, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 19917283, MOUSE PHENOTYPE ID: MGI:104663
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009536abnormal interstitial cell of Cajal morphology0self