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Details
Link-It Detail - Jax Mouse Phenotype - cardiac valve regurgitation
Debug Stats
  • ### Total Build Time: 49 ms 14.840 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 382 bytes
  • CONCEPT_SOLR_HIT_STATS gt=1 ms Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 280 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 185 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=1 ms Completed: 1 ms rowSize= 588 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.034 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.586 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 9.509 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
cardiac valve regurgitation MP:0009384
Definition (1)
the backward reflux of blood through a cardiac valve, due to insufficiency caused by disease, aging or congenital malformation
Synonyms (1)
"cardiac valve insufficiency" EXACT
Parents (1)
img abnormal cardiac valve physiology MP:0011926
Children (2)
img semilunar valve regurgitation MP:0006049
img atrioventricular valve regurgitation MP:0006046
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053855img abnormal cardiac valve physiology MP:0011926
Genes (18)

Species:
human : 18
SpeciesGeneGeneIdGene NameEvidence
HumanMUS8180198MUS81 structure-specific endonuclease subunit
INFERRED
HumanFGFRL153834fibroblast growth factor receptor-like 1
img Jax MP, Pubmed Id: 19383940, MOUSE PHENOTYPE ID: MGI:2150920
HumanPLCE151196phospholipase C, epsilon 1
INFERRED
HumanEFEMP230008EGF containing fibulin-like extracellular matrix protein 2
INFERRED
HumanHEY223493hairy/enhancer-of-split related with YRPW motif 2
INFERRED
HumanSEMA3C10512sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
INFERRED
HumanCITED210370Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
INFERRED
HumanNFATC14772nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
INFERRED
HumanLOX4015lysyl oxidase
INFERRED
HumanIDUA3425iduronidase, alpha-L-
INFERRED
HumanGJA12697gap junction protein, alpha 1, 43kDa
INFERRED
HumanGATA42626GATA binding protein 4
INFERRED
HumanERBB32065v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
INFERRED
HumanEPHA32042EPH receptor A3
INFERRED
HumanEGFR1956epidermal growth factor receptor
INFERRED
HumanBMPR1A657bone morphogenetic protein receptor, type IA
INFERRED
HumanARSB411arylsulfatase B
INFERRED
HumanJAG1182jagged 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009384cardiac valve regurgitation0self