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Details
Link-It Detail - Jax Mouse Phenotype - brain tumor
Debug Stats
  • ### Total Build Time: 64 ms 15.309 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 350 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 572 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.575 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=43 ms Completed: 43 ms rowSize= 10.709 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
brain tumor MP:0009277
Definition (1)
presence of abnormal rapidly proliferating cells in the brain, usually in the form of a distinct mass
Parents (1)
img increased nervous system tumor incidence MP:0010281
Children (1)
img medulloblastoma MP:0006283
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020068img increased nervous system tumor incidence MP:0010281
Genes (20)

Species:
human : 20
SpeciesGeneGeneIdGene NameEvidence
HumanNHEJ179840nonhomologous end-joining factor 1
INFERRED
HumanSUFU51684suppressor of fused homolog (Drosophila)
INFERRED
HumanCXCR610663chemokine (C-X-C motif) receptor 6
INFERRED
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
INFERRED
HumanXRCC47518X-ray repair complementing defective repair in Chinese hamster cells 4
INFERRED
HumanXRCC27516X-ray repair complementing defective repair in Chinese hamster cells 2
INFERRED
HumanTP537157tumor protein p53
INFERRED
HumanSMARCB16598SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Click here to display 25 evidence detail records.
HumanRB15925retinoblastoma 1
Click here to display 25 evidence detail records.
HumanRAG15896recombination activating gene 1
INFERRED
HumanPTEN5728phosphatase and tensin homolog
Click here to display 25 evidence detail records.
HumanPTCH15727patched 1
INFERRED
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
INFERRED
HumanNF14763neurofibromin 1
Click here to display 25 evidence detail records.
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Click here to display 25 evidence detail records.
HumanLIG43981ligase IV, DNA, ATP-dependent
INFERRED
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
INFERRED
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
Click here to display 25 evidence detail records.
HumanBUB1699BUB1 mitotic checkpoint serine/threonine kinase
Click here to display 25 evidence detail records.
HumanBRCA2675breast cancer 2, early onset
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009277brain tumor0self