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Details
Link-It Detail - Jax Mouse Phenotype - abnormal thymocyte apoptosis
Debug Stats
  • ### Total Build Time: 70 ms 38.554 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 384 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 272 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 1.464 KB
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 1.027 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=8 ms Completed: 8 ms rowSize= 6.908 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=40 ms Completed: 40 ms rowSize= 27.203 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal thymocyte apoptosis MP:0009258
Definition (1)
change in the timing or the number of immature T cells located in the thymus that are undergoing programmed cell death
Parents (3)
img abnormal T cell apoptosis MP:0006412
img abnormal thymus physiology MP:0003763
img abnormal apoptosis MP:0001648
Children (2)
img decreased thymocyte apoptosis MP:0009542
img increased thymocyte apoptosis MP:0009541
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal T cell apoptosis MP:0006412
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal T cell apoptosis MP:0006412
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal thymus physiology MP:0003763
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053975img abnormal thymus physiology MP:0003763
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal apoptosis MP:0001648
Genes (47)

Species:
human : 47
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNHEJ179840nonhomologous end-joining factor 1
INFERRED
HumanTMEM10979073transmembrane protein 109
INFERRED
HumanBCL11B64919B-cell CLL/lymphoma 11B (zinc finger protein)
INFERRED
HumanPERP64065PERP, TP53 apoptosis effector
INFERRED
HumanBIRC657448baculoviral IAP repeat containing 6
INFERRED
HumanTWSG157045twisted gastrulation homolog 1 (Drosophila)
INFERRED
HumanFAIM55179Fas apoptotic inhibitory molecule
INFERRED
HumanKLF1351621Kruppel-like factor 13
INFERRED
HumanKIFAP322920kinesin-associated protein 3
INFERRED
HumanCOPS610980COP9 signalosome subunit 6
INFERRED
HumanNDRG110397N-myc downstream regulated 1
INFERRED
HumanSTUB110273STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
INFERRED
HumanCFLAR8837CASP8 and FADD-like apoptosis regulator
INFERRED
HumanFADD8772Fas (TNFRSF6)-associated via death domain
img Jax MP, Pubmed Id: 9708736, MOUSE PHENOTYPE ID: MGI:1277950
img Jax MP, Pubmed Id: 20615958, MOUSE PHENOTYPE ID: MGI:109324
img Jax MP, Pubmed Id: 12909629, MOUSE PHENOTYPE ID: MGI:98834
img Jax MP, Pubmed Id: 12151339, MOUSE PHENOTYPE ID: MGI:1346870
img Jax MP, Pubmed Id: 12165507, MOUSE PHENOTYPE ID: MGI:95824
img Jax MP, Pubmed Id: 9708735, MOUSE PHENOTYPE ID: MGI:1277950
HumanFOXN18456forkhead box N1
INFERRED
HumanUSP47375ubiquitin specific peptidase 4 (proto-oncogene)
INFERRED
HumanTRAF27186TNF receptor-associated factor 2
INFERRED
HumanTP737161tumor protein p73
INFERRED
HumanTP537157tumor protein p53
img Jax MP, Pubmed Id: 12151339, MOUSE PHENOTYPE ID: MGI:1346870
img Jax MP, Pubmed Id: 12909629, MOUSE PHENOTYPE ID: MGI:98834
img Jax MP, Pubmed Id: 9708736, MOUSE PHENOTYPE ID: MGI:1277950
img Jax MP, Pubmed Id: 12165507, MOUSE PHENOTYPE ID: MGI:95824
img Jax MP, Pubmed Id: 9708735, MOUSE PHENOTYPE ID: MGI:1277950
img Jax MP, Pubmed Id: 20615958, MOUSE PHENOTYPE ID: MGI:109324
HumanMAP3K76885mitogen-activated protein kinase kinase kinase 7
INFERRED
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
INFERRED
HumanST146768suppression of tumorigenicity 14 (colon carcinoma)
INFERRED
HumanRORC6097RAR-related orphan receptor C
INFERRED
HumanMAP2K65608mitogen-activated protein kinase kinase 6
img Jax MP, Pubmed Id: 20615958, MOUSE PHENOTYPE ID: MGI:109324
img Jax MP, Pubmed Id: 9708735, MOUSE PHENOTYPE ID: MGI:1277950
img Jax MP, Pubmed Id: 12909629, MOUSE PHENOTYPE ID: MGI:98834
img Jax MP, Pubmed Id: 12165507, MOUSE PHENOTYPE ID: MGI:95824
img Jax MP, Pubmed Id: 9708736, MOUSE PHENOTYPE ID: MGI:1277950
img Jax MP, Pubmed Id: 12151339, MOUSE PHENOTYPE ID: MGI:1346870
HumanPRKDC5591protein kinase, DNA-activated, catalytic polypeptide
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009258abnormal thymocyte apoptosis0self