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Details
Link-It Detail - Jax Mouse Phenotype - abnormal tumor necrosis factor level
Debug Stats
  • ### Total Build Time: 225 ms 22.470 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 400 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 507 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 200 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=17 ms Completed: 17 ms rowSize= 578 bytes
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 605 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=13 ms Completed: 13 ms rowSize= 2.911 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=178 ms Completed: 178 ms rowSize= 16.004 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.174 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal tumor necrosis factor level MP:0008752
Definition (1)
deviation from the normal levels of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms (1)
"abnormal tumor necrosis factor alpha level" EXACT
Parents (1)
img abnormal cytokine level MP:0008713
Children (1)
img abnormal circulating tumor necrosis factor level MP:0008552
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal cytokine level MP:0008713
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal cytokine level MP:0008713
Genes (136)

Species:
human : 136
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 66 evidence detail records.
HumanNLRC3197358NLR family, CARD domain containing 3
INFERRED
HumanBBS12166379Bardet-Biedl syndrome 12
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 66 evidence detail records.
HumanSLAMF6114836SLAM family member 6
INFERRED
HumanPGLYRP2114770peptidoglycan recognition protein 2
Click here to display 66 evidence detail records.
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanZC3H12A80149zinc finger CCCH-type containing 12A
INFERRED
HumanRHBDF279651rhomboid 5 homolog 2 (Drosophila)
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanNOD264127nucleotide-binding oligomerization domain containing 2
Click here to display 66 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanTBC1D2355773TBC1 domain family, member 23
Click here to display 66 evidence detail records.
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanTREM254209triggering receptor expressed on myeloid cells 2
Click here to display 66 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanFOXP350943forkhead box P3
Click here to display 66 evidence detail records.
HumanIL2250616interleukin 22
INFERRED
HumanTBX2130009T-box 21
Click here to display 66 evidence detail records.
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanHTRA227429HtrA serine peptidase 2
Click here to display 66 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008752abnormal tumor necrosis factor level0self