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Details
Link-It Detail - Jax Mouse Phenotype - abnormal tumor necrosis factor level
Debug Stats
  • ### Total Build Time: 296 ms 22.446 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 400 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 507 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 176 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=14 ms Completed: 14 ms rowSize= 578 bytes
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 605 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 2.911 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=255 ms Completed: 255 ms rowSize= 16.004 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.174 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal tumor necrosis factor level MP:0008752
Definition (1)
deviation from the normal levels of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms (1)
"abnormal TNF level" EXACT
Parents (1)
img abnormal cytokine level MP:0008713
Children (1)
img abnormal circulating tumor necrosis factor level MP:0008552
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal cytokine level MP:0008713
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal cytokine level MP:0008713
Genes (136)

Species:
human : 136
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 66 evidence detail records.
HumanNLRC3197358NLR family, CARD domain containing 3
INFERRED
HumanBBS12166379Bardet-Biedl syndrome 12
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 66 evidence detail records.
HumanSLAMF6114836SLAM family member 6
INFERRED
HumanPGLYRP2114770peptidoglycan recognition protein 2
Click here to display 66 evidence detail records.
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanZC3H12A80149zinc finger CCCH-type containing 12A
INFERRED
HumanRHBDF279651rhomboid 5 homolog 2 (Drosophila)
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanNOD264127nucleotide-binding oligomerization domain containing 2
Click here to display 66 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanTBC1D2355773TBC1 domain family, member 23
Click here to display 66 evidence detail records.
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanTREM254209triggering receptor expressed on myeloid cells 2
Click here to display 66 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanFOXP350943forkhead box P3
Click here to display 66 evidence detail records.
HumanIL2250616interleukin 22
INFERRED
HumanTBX2130009T-box 21
Click here to display 66 evidence detail records.
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanHTRA227429HtrA serine peptidase 2
Click here to display 66 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008752abnormal tumor necrosis factor level0self