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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to endotoxin shock
Debug Stats
  • ### Total Build Time: 256 ms 22.075 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 363 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 197 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 583 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.573 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=249 ms Completed: 249 ms rowSize= 17.648 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased susceptibility to endotoxin shock MP:0008734
Definition (1)
less than the expected early reaction of the microcirculation to endotoxins such as LPS, characterized by movement of fluid and leukocytes from the blood into extravascular tissues and often resulting in death
Synonyms (1)
"increased resistance to endotoxin shock" EXACT
Parents (1)
img decreased acute inflammation MP:0005087
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img decreased acute inflammation MP:0005087
Genes (68)

Species:
human : 68
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SpeciesGeneGeneIdGene NameEvidence
HumanNLRP10338322NLR family, pyrin domain containing 10
Click here to display 114 evidence detail records.
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 114 evidence detail records.
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Click here to display 114 evidence detail records.
HumanNLRP3114548NLR family, pyrin domain containing 3
Click here to display 114 evidence detail records.
HumanIL3390865interleukin 33
Click here to display 114 evidence detail records.
HumanNOD264127nucleotide-binding oligomerization domain containing 2
Click here to display 114 evidence detail records.
HumanPELI157162pellino E3 ubiquitin protein ligase 1
Click here to display 114 evidence detail records.
HumanTERF2IP54386telomeric repeat binding factor 2, interacting protein
Click here to display 114 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
Click here to display 114 evidence detail records.
HumanPYCARD29108PYD and CARD domain containing
Click here to display 114 evidence detail records.
HumanCLIC425932chloride intracellular channel 4
Click here to display 114 evidence detail records.
HumanGCA25801grancalcin, EF-hand calcium binding protein
Click here to display 114 evidence detail records.
HumanLY9623643lymphocyte antigen 96
Click here to display 114 evidence detail records.
HumanPLA2R122925phospholipase A2 receptor 1, 180kDa
Click here to display 114 evidence detail records.
HumanNR1H310062nuclear receptor subfamily 1, group H, member 3
Click here to display 114 evidence detail records.
HumanAPBA39546amyloid beta (A4) precursor protein-binding, family A, member 3
Click here to display 114 evidence detail records.
HumanLITAF9516lipopolysaccharide-induced TNF factor
Click here to display 114 evidence detail records.
HumanMAPKAPK29261mitogen-activated protein kinase-activated protein kinase 2
Click here to display 114 evidence detail records.
HumanSOCS39021suppressor of cytokine signaling 3
Click here to display 114 evidence detail records.
HumanSPHK18877sphingosine kinase 1
Click here to display 114 evidence detail records.
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Click here to display 114 evidence detail records.
HumanIKBKG8517inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Click here to display 114 evidence detail records.
HumanNSMAF8439neutral sphingomyelinase (N-SMase) activation associated factor
Click here to display 114 evidence detail records.
HumanTRPV17442transient receptor potential cation channel, subfamily V, member 1
Click here to display 114 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
Click here to display 114 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008734decreased susceptibility to endotoxin shock0self