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Details
Link-It Detail - Jax Mouse Phenotype - increased interleukin-4 secretion
Debug Stats
  • ### Total Build Time: 418 ms 21.842 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 453 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 182 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 587 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 1.577 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=396 ms Completed: 396 ms rowSize= 17.363 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased interleukin-4 secretion MP:0008699
Definition (1)
increase in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms (1)
"increased IL-4 secretion" EXACT
Parents (1)
img abnormal interleukin-4 secretion MP:0008698
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal interleukin-4 secretion MP:0008698
Genes (52)

Species:
human : 52
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCD300LF146722CD300 molecule-like family member f
Click here to display 80 evidence detail records.
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
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HumanRNF12879589ring finger protein 128, E3 ubiquitin protein ligase
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HumanBHLHE4179365basic helix-loop-helix family, member e41
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HumanAHNAK79026AHNAK nucleoprotein
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HumanSAMSN164092SAM domain, SH3 domain and nuclear localization signals 1
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HumanGPR8453831G protein-coupled receptor 84
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HumanSIRT751547sirtuin 7
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HumanFOXP350943forkhead box P3
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HumanCD27429126CD274 molecule
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HumanTNFRSF2127242tumor necrosis factor receptor superfamily, member 21
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HumanLAT27040linker for activation of T cells
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HumanHAVCR126762hepatitis A virus cellular receptor 1
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HumanHCST10870hematopoietic cell signal transducer
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HumanKLF210365Kruppel-like factor 2 (lung)
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HumanIL27RA9466interleukin 27 receptor, alpha
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HumanSH2D2A9047SH2 domain containing 2A
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HumanTNFSF138741tumor necrosis factor (ligand) superfamily, member 13
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HumanEOMES8320eomesodermin
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HumanSTK46789serine/threonine kinase 4
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HumanSTAT46775signal transducer and activator of transcription 4
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HumanSPP16696secreted phosphoprotein 1
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HumanEIF2AK25610eukaryotic translation initiation factor 2-alpha kinase 2
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HumanPPIA5478peptidylprolyl isomerase A (cyclophilin A)
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HumanPOU2AF15450POU class 2 associating factor 1
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XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008699increased interleukin-4 secretion0self