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Details
Link-It Detail - Jax Mouse Phenotype - decreased interleukin-18 secretion
Debug Stats
  • ### Total Build Time: 23 ms 55.676 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 375 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 210 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 588 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.578 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 51.241 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased interleukin-18 secretion MP:0008685
Definition (1)
reduction in the production or release of a cytokine which enhances the cytotoxic activity of NK cells and cytotoxic T-cells and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity
Synonyms (1)
"decreased interferon-gamma inducing factor secretion" EXACT
Parents (1)
img abnormal interleukin-18 secretion MP:0008683
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal interleukin-18 secretion MP:0008683
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanNLRP6171389NLR family, pyrin domain containing 6
img Jax MP, Pubmed Id: 15190255, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22695634, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 14693703, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 16407890, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 15507117, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22461501, MOUSE PHENOTYPE ID: MGI:2429943
img Jax MP, Pubmed Id: 21565393, MOUSE PHENOTYPE ID: MGI:2141990
img Jax MP, Pubmed Id: 20457908, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 10491411, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 20351692, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 16547271, MOUSE PHENOTYPE ID: MGI:1931465
HumanGBP5115362guanylate binding protein 5
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 20351692, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 22695634, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 20457908, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22461501, MOUSE PHENOTYPE ID: MGI:2429943
img Jax MP, Pubmed Id: 14693703, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 16407890, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 15507117, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 10491411, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 15190255, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 21565393, MOUSE PHENOTYPE ID: MGI:2141990
img Jax MP, Pubmed Id: 16547271, MOUSE PHENOTYPE ID: MGI:1931465
HumanPYCARD29108PYD and CARD domain containing
img Jax MP, Pubmed Id: 15507117, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22695634, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 16547271, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 20351692, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 20457908, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 14693703, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 16407890, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22461501, MOUSE PHENOTYPE ID: MGI:2429943
img Jax MP, Pubmed Id: 10491411, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 15190255, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 21565393, MOUSE PHENOTYPE ID: MGI:2141990
HumanAIM29447absent in melanoma 2
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 14693703, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 10491411, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 21565393, MOUSE PHENOTYPE ID: MGI:2141990
img Jax MP, Pubmed Id: 15507117, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22461501, MOUSE PHENOTYPE ID: MGI:2429943
img Jax MP, Pubmed Id: 16547271, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 16407890, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22695634, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 15190255, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 20351692, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 20457908, MOUSE PHENOTYPE ID: MGI:2686159
HumanCASP4837caspase 4, apoptosis-related cysteine peptidase
img Jax MP, Pubmed Id: 20351692, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 16547271, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 20457908, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 14693703, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22461501, MOUSE PHENOTYPE ID: MGI:2429943
img Jax MP, Pubmed Id: 10491411, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 16407890, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 22002608, MOUSE PHENOTYPE ID: MGI:107700
img Jax MP, Pubmed Id: 22695634, MOUSE PHENOTYPE ID: MGI:2686159
img Jax MP, Pubmed Id: 15507117, MOUSE PHENOTYPE ID: MGI:1931465
img Jax MP, Pubmed Id: 21565393, MOUSE PHENOTYPE ID: MGI:2141990
img Jax MP, Pubmed Id: 15190255, MOUSE PHENOTYPE ID: MGI:1931465
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008685decreased interleukin-18 secretion0self