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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interleukin-12 secretion
Debug Stats
  • ### Total Build Time: 18 ms 20.548 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 585 bytes
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 14.574 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interleukin-12 secretion MP:0008662
Definition (1)
anomaly in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells
Synonyms (1)
"abnormal IL12 secretion" EXACT
Parents (1)
img abnormal interleukin secretion MP:0008568
Children (3)
img increased interleukin-12 secretion MP:0008663
img decreased interleukin-12 secretion MP:0008664
img abnormal interleukin-12a secretion MP:0008665
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interleukin secretion MP:0008568
Genes (59)

Species:
human : 59
Page Size
Current 25
  Page 1 of 3
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCD300LF146722CD300 molecule-like family member f
INFERRED
HumanSLC15A4121260solute carrier family 15 (oligopeptide transporter), member 4
INFERRED
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanPINK165018PTEN induced putative kinase 1
INFERRED
HumanNFKBIZ64332nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
INFERRED
HumanSAMSN164092SAM domain, SH3 domain and nuclear localization signals 1
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanMARCH155016membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
INFERRED
HumanSIRT751547sirtuin 7
INFERRED
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
INFERRED
HumanCLIC425932chloride intracellular channel 4
INFERRED
HumanMAP4K111184mitogen-activated protein kinase kinase kinase kinase 1
INFERRED
HumanTRAFD110906TRAF-type zinc finger domain containing 1
INFERRED
HumanTLR610333toll-like receptor 6
INFERRED
HumanTNIP110318TNFAIP3 interacting protein 1
INFERRED
HumanTRIB110221tribbles homolog 1 (Drosophila)
INFERRED
HumanAPBA39546amyloid beta (A4) precursor protein-binding, family A, member 3
INFERRED
HumanRPS6KA59252ribosomal protein S6 kinase, 90kDa, polypeptide 5
INFERRED
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
INFERRED
HumanTNFSF128742tumor necrosis factor (ligand) superfamily, member 12
INFERRED
HumanLAT27462linker for activation of T cells family, member 2
INFERRED
HumanTRPM27226transient receptor potential cation channel, subfamily M, member 2
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008662abnormal interleukin-12 secretion0self