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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating interleukin-1 alpha level
Debug Stats
  • ### Total Build Time: 38 ms 43.221 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 422 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 412 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 190 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 601 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=7 ms Completed: 7 ms rowSize= 4.325 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 35.972 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.185 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased circulating interleukin-1 alpha level MP:0008638
Definition (1)
increase in the amount in the blood of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active
Synonyms (1)
"increased circulating IL1a level" EXACT
Parents (1)
img abnormal circulating interleukin-1 alpha level MP:0008637
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-1 alpha level MP:0008637
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal circulating interleukin-1 alpha level MP:0008637
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537611img abnormal circulating interleukin-1 alpha level MP:0008637
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanTREM154210triggering receptor expressed on myeloid cells 1
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930005
img Jax MP, Pubmed Id: 23293022, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 20696914, MOUSE PHENOTYPE ID: MGI:104741
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96537
img Jax MP, Pubmed Id: 16936011, MOUSE PHENOTYPE ID: MGI:88042
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930003
img Jax MP, Pubmed Id: 20200541, MOUSE PHENOTYPE ID: MGI:4456268
HumanNFKBIA4792nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
img Jax MP, Pubmed Id: 20696914, MOUSE PHENOTYPE ID: MGI:104741
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 20200541, MOUSE PHENOTYPE ID: MGI:4456268
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930003
img Jax MP, Pubmed Id: 23293022, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 16936011, MOUSE PHENOTYPE ID: MGI:88042
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930005
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96537
HumanIL10RA3587interleukin 10 receptor, alpha
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930003
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 16936011, MOUSE PHENOTYPE ID: MGI:88042
img Jax MP, Pubmed Id: 23293022, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 20200541, MOUSE PHENOTYPE ID: MGI:4456268
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96537
img Jax MP, Pubmed Id: 20696914, MOUSE PHENOTYPE ID: MGI:104741
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930005
HumanIL103586interleukin 10
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 20696914, MOUSE PHENOTYPE ID: MGI:104741
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930003
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 23293022, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96537
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930005
img Jax MP, Pubmed Id: 16936011, MOUSE PHENOTYPE ID: MGI:88042
img Jax MP, Pubmed Id: 20200541, MOUSE PHENOTYPE ID: MGI:4456268
HumanAPEX1328APEX nuclease (multifunctional DNA repair enzyme) 1
img Jax MP, Pubmed Id: 20200541, MOUSE PHENOTYPE ID: MGI:4456268
img Jax MP, Pubmed Id: 23293022, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 16936011, MOUSE PHENOTYPE ID: MGI:88042
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96537
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930003
img Jax MP, Pubmed Id: 23241959, MOUSE PHENOTYPE ID: MGI:1930005
img Jax MP, Pubmed Id: 19941312, MOUSE PHENOTYPE ID: MGI:96538
img Jax MP, Pubmed Id: 20696914, MOUSE PHENOTYPE ID: MGI:104741
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008638increased circulating interleukin-1 alpha level0self