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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin-1 alpha level
Debug Stats
  • ### Total Build Time: 32 ms 12.902 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 420 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.062 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 4.306 KB
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  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 4.629 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.184 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal circulating interleukin-1 alpha level MP:0008637
Definition (1)
anomaly in the amount in the blood of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active
Synonyms (1)
"abnormal circulating IL1a level" EXACT
Parents (1)
img abnormal circulating interleukin-1 level MP:0008589
Children (2)
img increased circulating interleukin-1 alpha level MP:0008638
img decreased circulating interleukin-1 alpha level MP:0008639
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal circulating interleukin-1 level MP:0008589
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-1 level MP:0008589
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin-1 level MP:0008589
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanIL2250616interleukin 22
INFERRED
HumanTNF7124tumor necrosis factor
INFERRED
HumanNFKBIA4792nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
INFERRED
HumanIL10RA3587interleukin 10 receptor, alpha
INFERRED
HumanIL103586interleukin 10
INFERRED
HumanIL1A3552interleukin 1, alpha
INFERRED
HumanCASP4837caspase 4, apoptosis-related cysteine peptidase
INFERRED
HumanAPEX1328APEX nuclease (multifunctional DNA repair enzyme) 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008637abnormal circulating interleukin-1 alpha level0self