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Details
Link-It Detail - Jax Mouse Phenotype - decreased circulating interleukin-4 level
Debug Stats
  • ### Total Build Time: 23 ms 15.976 KB
  • CONCEPT_NAME gt=3 ms Completed: 2 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 452 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 206 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 4.306 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 8.715 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased circulating interleukin-4 level MP:0008603
Definition (1)
reduction in the amount in the blood of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms (1)
"reduced circulating B-cell growth factor-1 level" EXACT
Parents (1)
img abnormal circulating interleukin-4 level MP:0008601
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin-4 level MP:0008601
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal circulating interleukin-4 level MP:0008601
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-4 level MP:0008601
Genes (14)

Species:
human : 14
SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
Click here to display 16 evidence detail records.
HumanTSLP85480thymic stromal lymphopoietin
Click here to display 16 evidence detail records.
HumanNFATC2IP84901nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
Click here to display 16 evidence detail records.
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 16 evidence detail records.
HumanCXCL1658191chemokine (C-X-C motif) ligand 16
Click here to display 16 evidence detail records.
HumanICOS29851inducible T-cell co-stimulator
Click here to display 16 evidence detail records.
HumanMAP3K149020mitogen-activated protein kinase kinase kinase 14
Click here to display 16 evidence detail records.
HumanRELB5971v-rel avian reticuloendotheliosis viral oncogene homolog B
Click here to display 16 evidence detail records.
HumanIL23558interleukin 2
Click here to display 16 evidence detail records.
HumanGATA12623GATA binding protein 1 (globin transcription factor 1)
Click here to display 16 evidence detail records.
HumanFCER1A2205Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Click here to display 16 evidence detail records.
HumanCCR31232chemokine (C-C motif) receptor 3
Click here to display 16 evidence detail records.
HumanCD28940CD28 molecule
Click here to display 16 evidence detail records.
HumanCD19930CD19 molecule
Click here to display 16 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008603decreased circulating interleukin-4 level0self