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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating interleukin-6 level
Debug Stats
  • ### Total Build Time: 468 ms 24.535 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 408 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 213 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=15 ms Completed: 15 ms rowSize= 595 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 4.306 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=437 ms Completed: 437 ms rowSize= 17.311 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased circulating interleukin-6 level MP:0008596
Definition (1)
increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms (1)
"increased circulating B cell stimulatory factor-2 level" EXACT
Parents (1)
img abnormal circulating interleukin-6 level MP:0008595
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin-6 level MP:0008595
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal circulating interleukin-6 level MP:0008595
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-6 level MP:0008595
Genes (62)

Species:
human : 62
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SpeciesGeneGeneIdGene NameEvidence
HumanNLRC3197358NLR family, CARD domain containing 3
Click here to display 96 evidence detail records.
HumanNLRP3114548NLR family, pyrin domain containing 3
Click here to display 96 evidence detail records.
HumanNLRX179671NLR family member X1
Click here to display 96 evidence detail records.
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
Click here to display 96 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
Click here to display 96 evidence detail records.
HumanTBC1D2355773TBC1 domain family, member 23
Click here to display 96 evidence detail records.
HumanTREM154210triggering receptor expressed on myeloid cells 1
Click here to display 96 evidence detail records.
HumanING451147inhibitor of growth family, member 4
Click here to display 96 evidence detail records.
HumanFOXP350943forkhead box P3
Click here to display 96 evidence detail records.
HumanTBK129110TANK-binding kinase 1
Click here to display 96 evidence detail records.
HumanSIRT323410sirtuin 3
Click here to display 96 evidence detail records.
HumanSMG123049SMG1 phosphatidylinositol 3-kinase-related kinase
Click here to display 96 evidence detail records.
HumanUSP1811274ubiquitin specific peptidase 18
Click here to display 96 evidence detail records.
HumanTRAFD110906TRAF-type zinc finger domain containing 1
Click here to display 96 evidence detail records.
HumanRAMP110267receptor (G protein-coupled) activity modifying protein 1
Click here to display 96 evidence detail records.
HumanBAG49530BCL2-associated athanogene 4
Click here to display 96 evidence detail records.
HumanIL27RA9466interleukin 27 receptor, alpha
Click here to display 96 evidence detail records.
HumanRPS6KA59252ribosomal protein S6 kinase, 90kDa, polypeptide 5
Click here to display 96 evidence detail records.
HumanSTX118676syntaxin 11
Click here to display 96 evidence detail records.
HumanNCOA38202nuclear receptor coactivator 3
Click here to display 96 evidence detail records.
HumanLAT27462linker for activation of T cells family, member 2
Click here to display 96 evidence detail records.
HumanTP537157tumor protein p53
Click here to display 96 evidence detail records.
HumanTNFAIP37128tumor necrosis factor, alpha-induced protein 3
Click here to display 96 evidence detail records.
HumanTLR47099toll-like receptor 4
Click here to display 96 evidence detail records.
HumanTHBD7056thrombomodulin
Click here to display 96 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008596increased circulating interleukin-6 level0self