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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin-6 level
Debug Stats
  • ### Total Build Time: 78 ms 22.936 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 407 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 216 bytes
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  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 4.299 KB
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  • CONCEPT_GENES gt=45 ms Completed: 45 ms rowSize= 14.678 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal circulating interleukin-6 level MP:0008595
Definition (1)
anomaly in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms (1)
"abnormal circulating B-cell differentiation factor-2 level" EXACT
Parents (1)
img abnormal circulating interleukin level MP:0008588
Children (2)
img increased circulating interleukin-6 level MP:0008596
img decreased circulating interleukin-6 level MP:0008597
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interleukin level MP:0008588
Genes (101)

Species:
human : 101
Page Size
Current 25
  Page 1 of 5
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanTMEM173340061transmembrane protein 173
INFERRED
HumanTAB3257397TGF-beta activated kinase 1/MAP3K7 binding protein 3
INFERRED
HumanNLRC3197358NLR family, CARD domain containing 3
INFERRED
HumanBBS12166379Bardet-Biedl syndrome 12
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanPGLYRP2114770peptidoglycan recognition protein 2
INFERRED
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
INFERRED
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanNLRX179671NLR family member X1
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanTBC1D2355773TBC1 domain family, member 23
INFERRED
HumanTOLLIP54472toll interacting protein
INFERRED
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanING451147inhibitor of growth family, member 4
INFERRED
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanFOXP350943forkhead box P3
INFERRED
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanHSPB826353heat shock 22kDa protein 8
INFERRED
HumanCLIC425932chloride intracellular channel 4
INFERRED
HumanSIRT323410sirtuin 3
INFERRED
HumanSMG123049SMG1 phosphatidylinositol 3-kinase-related kinase
INFERRED
HumanUSP1811274ubiquitin specific peptidase 18
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008595abnormal circulating interleukin-6 level0self