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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin-10 level
Debug Stats
  • ### Total Build Time: 50 ms 19.984 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 192 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.053 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=25 ms Completed: 25 ms rowSize= 4.299 KB
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  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 11.775 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.179 KB
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  • Reload Stats
Jax Mouse Phenotype (1)
abnormal circulating interleukin-10 level MP:0008590
Definition (1)
anomaly in the amount in the blood of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation
Synonyms (1)
"abnormal circulating CSIF-10 level" EXACT
Parents (1)
img abnormal circulating interleukin level MP:0008588
Children (2)
img decreased circulating interleukin-10 level MP:0008594
img increased circulating interleukin-10 level MP:0008593
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin level MP:0008588
Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanFOXP350943forkhead box P3
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanSIRT323410sirtuin 3
INFERRED
HumanRPS6KA59252ribosomal protein S6 kinase, 90kDa, polypeptide 5
INFERRED
HumanSTK116794serine/threonine kinase 11
INFERRED
HumanCCL136357chemokine (C-C motif) ligand 13
INFERRED
HumanPTPN65777protein tyrosine phosphatase, non-receptor type 6
INFERRED
HumanPRF15551perforin 1 (pore forming protein)
INFERRED
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
INFERRED
HumanOLR14973oxidized low density lipoprotein (lectin-like) receptor 1
INFERRED
HumanMYD884615myeloid differentiation primary response 88
INFERRED
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED
HumanLDLR3949low density lipoprotein receptor
INFERRED
HumanITGAL3683integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
INFERRED
HumanIRF13659interferon regulatory factor 1
img Jax MP, Pubmed Id: 12807824, MOUSE PHENOTYPE ID: MGI:96590
HumanIL103586interleukin 10
INFERRED
HumanIL63569interleukin 6 (interferon, beta 2)
INFERRED
HumanFOS2353FBJ murine osteosarcoma viral oncogene homolog
INFERRED
HumanDUSP11843dual specificity phosphatase 1
INFERRED
HumanCD19930CD19 molecule
INFERRED
HumanAPEX1328APEX nuclease (multifunctional DNA repair enzyme) 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008590abnormal circulating interleukin-10 level0self