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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interferon-alpha secretion
Debug Stats
  • ### Total Build Time: 15 ms 14.194 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 398 bytes
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Jax Mouse Phenotype (1)
abnormal interferon-alpha secretion MP:0008557
Definition (1)
anomaly in the production or release of one of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells that has antiviral activity and activates natural killer cells and B cells
Synonyms (1)
"abnormal alpha-IFN secretion" EXACT
Parents (1)
img abnormal interferon secretion MP:0008555
Children (2)
img decreased interferon-alpha secretion MP:0008563
img increased interferon-alpha secretion MP:0008562
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interferon secretion MP:0008555
Genes (18)

Species:
human : 18
SpeciesGeneGeneIdGene NameEvidence
HumanRSAD291543radical S-adenosyl methionine domain containing 2
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanIFIH164135interferon induced with helicase C domain 1
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanPACSIN129993protein kinase C and casein kinase substrate in neurons 1
INFERRED
HumanIRF910379interferon regulatory factor 9
INFERRED
HumanTANK10010TRAF family member-associated NFKB activator
INFERRED
HumanMYD884615myeloid differentiation primary response 88
INFERRED
HumanIRF53663interferon regulatory factor 5
INFERRED
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
INFERRED
HumanIFNA133447interferon, alpha 13
INFERRED
HumanIFNA13439interferon, alpha 1
INFERRED
HumanFLT32322fms-related tyrosine kinase 3
INFERRED
HumanMAPK141432mitogen-activated protein kinase 14
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008557abnormal interferon-alpha secretion0self