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Details
Link-It Detail - Jax Mouse Phenotype - decreased circulating tumor necrosis factor level
Debug Stats
  • ### Total Build Time: 111 ms 24.512 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 426 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 511 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 190 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 603 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 4.328 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=89 ms Completed: 89 ms rowSize= 17.155 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.187 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased circulating tumor necrosis factor level MP:0008554
Definition (1)
reduction in the amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms (1)
"decreased circulating TNFA level" EXACT
Parents (1)
img abnormal circulating tumor necrosis factor level MP:0008552
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating tumor necrosis factor level MP:0008552
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating tumor necrosis factor level MP:0008552
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating tumor necrosis factor level MP:0008552
Genes (38)

Species:
human : 38
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanBBS12166379Bardet-Biedl syndrome 12
Click here to display 57 evidence detail records.
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 57 evidence detail records.
HumanRHBDF279651rhomboid 5 homolog 2 (Drosophila)
Click here to display 57 evidence detail records.
HumanPELI157162pellino E3 ubiquitin protein ligase 1
Click here to display 57 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
Click here to display 57 evidence detail records.
HumanIL2250616interleukin 22
Click here to display 57 evidence detail records.
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
Click here to display 57 evidence detail records.
HumanCLIC425932chloride intracellular channel 4
Click here to display 57 evidence detail records.
HumanAPBA39546amyloid beta (A4) precursor protein-binding, family A, member 3
Click here to display 57 evidence detail records.
HumanMAPKAPK29261mitogen-activated protein kinase-activated protein kinase 2
Click here to display 57 evidence detail records.
HumanTRADD8717TNFRSF1A-associated via death domain
Click here to display 57 evidence detail records.
HumanFOXN18456forkhead box N1
Click here to display 57 evidence detail records.
HumanTNF7124tumor necrosis factor
Click here to display 57 evidence detail records.
HumanTLR27097toll-like receptor 2
Click here to display 57 evidence detail records.
HumanTHBD7056thrombomodulin
Click here to display 57 evidence detail records.
HumanADAM176868ADAM metallopeptidase domain 17
Click here to display 57 evidence detail records.
HumanSIGLEC16614sialic acid binding Ig-like lectin 1, sialoadhesin
Click here to display 57 evidence detail records.
HumanS100A96280S100 calcium binding protein A9
Click here to display 57 evidence detail records.
HumanPRKCE5581protein kinase C, epsilon
Click here to display 57 evidence detail records.
HumanNPY1R4886neuropeptide Y receptor Y1
Click here to display 57 evidence detail records.
HumanNFKBIB4793nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Click here to display 57 evidence detail records.
HumanMYD884615myeloid differentiation primary response 88
Click here to display 57 evidence detail records.
HumanMIF4282macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Click here to display 57 evidence detail records.
HumanLEP3952leptin
Click here to display 57 evidence detail records.
HumanIRF53663interferon regulatory factor 5
Click here to display 57 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008554decreased circulating tumor necrosis factor level0self