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Details
Link-It Detail - Jax Mouse Phenotype - abnormal lymph node germinal center morphology
Debug Stats
  • ### Total Build Time: 29 ms 18.692 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 420 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 433 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 604 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 590 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.594 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 13.771 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.184 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal lymph node germinal center morphology MP:0008522
Definition (1)
any structural anomaly of the area of the lymph node secondary follicle where antigen-activated B-cell blasts are stimulated by antigens and proliferate, with the immunoglobulin genes undergoing somatic hypermutation, before the cells migrate away as plasma cells or memory cells
Parents (1)
img abnormal lymph node secondary follicle morphology MP:0002346
Children (1)
img absent lymph node germinal center MP:0008523
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal lymph node secondary follicle morphology MP:0002346
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanUNC13D201294unc-13 homolog D (C. elegans)
INFERRED
HumanRC3H1149041ring finger and CCCH-type domains 1
Click here to display 17 evidence detail records.
HumanKLHL689857kelch-like family member 6
Click here to display 17 evidence detail records.
HumanIL21R50615interleukin 21 receptor
Click here to display 17 evidence detail records.
HumanLAT27040linker for activation of T cells
Click here to display 17 evidence detail records.
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
Click here to display 17 evidence detail records.
HumanCXCL1310563chemokine (C-X-C motif) ligand 13
Click here to display 17 evidence detail records.
HumanBHLHE408553basic helix-loop-helix family, member e40
Click here to display 17 evidence detail records.
HumanTRAF27186TNF receptor-associated factor 2
INFERRED
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED
HumanTNF7124tumor necrosis factor
INFERRED
HumanSELE6401selectin E
Click here to display 17 evidence detail records.
HumanPRKCD5580protein kinase C, delta
Click here to display 17 evidence detail records.
HumanPOU2AF15450POU class 2 associating factor 1
INFERRED
HumanNFKB24791nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
INFERRED
HumanIRF43662interferon regulatory factor 4
INFERRED
HumanINPP5D3635inositol polyphosphate-5-phosphatase, 145kDa
Click here to display 17 evidence detail records.
HumanIFNG3458interferon, gamma
INFERRED
HumanCCR71236chemokine (C-C motif) receptor 7
Click here to display 17 evidence detail records.
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Click here to display 17 evidence detail records.
HumanCD40LG959CD40 ligand
INFERRED
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
Click here to display 17 evidence detail records.
HumanCD37951CD37 molecule
Click here to display 17 evidence detail records.
HumanBTK695Bruton agammaglobulinemia tyrosine kinase
Click here to display 17 evidence detail records.
HumanBCL6604B-cell CLL/lymphoma 6
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008522abnormal lymph node germinal center morphology0self