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Details
Link-It Detail - Jax Mouse Phenotype - absent spleen germinal center
Debug Stats
  • ### Total Build Time: 162 ms 22.881 KB
  • CONCEPT_NAME gt=6 ms Completed: 5 ms rowSize= 386 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 306 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=4 ms Completed: 4 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 597 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 2.947 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=118 ms Completed: 118 ms rowSize= 17.173 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
absent spleen germinal center MP:0008474
Definition (1)
absence of the area of the spleen secondary B follicle where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs
Synonyms (1)
"absent spleen follicle center" EXACT
Parents (1)
img abnormal spleen germinal center morphology MP:0002359
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal spleen germinal center morphology MP:0002359
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal spleen germinal center morphology MP:0002359
Genes (26)

Species:
human : 26
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanSHARPIN81858SHANK-associated RH domain interactor
Click here to display 55 evidence detail records.
HumanTRADD8717TNFRSF1A-associated via death domain
Click here to display 55 evidence detail records.
HumanSOCS18651suppressor of cytokine signaling 1
Click here to display 55 evidence detail records.
HumanTRAF27186TNF receptor-associated factor 2
Click here to display 55 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
Click here to display 55 evidence detail records.
HumanTNF7124tumor necrosis factor
Click here to display 55 evidence detail records.
HumanSPIB6689Spi-B transcription factor (Spi-1/PU.1 related)
Click here to display 55 evidence detail records.
HumanPOU2AF15450POU class 2 associating factor 1
Click here to display 55 evidence detail records.
HumanPIK3CD5293phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Click here to display 55 evidence detail records.
HumanNFKBIA4792nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Click here to display 55 evidence detail records.
HumanNFKB24791nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Click here to display 55 evidence detail records.
HumanLTBR4055lymphotoxin beta receptor (TNFR superfamily, member 3)
Click here to display 55 evidence detail records.
HumanLTB4050lymphotoxin beta (TNF superfamily, member 3)
Click here to display 55 evidence detail records.
HumanLTA4049lymphotoxin alpha
Click here to display 55 evidence detail records.
HumanIRF43662interferon regulatory factor 4
Click here to display 55 evidence detail records.
HumanIL2RG3561interleukin 2 receptor, gamma
Click here to display 55 evidence detail records.
HumanIFNG3458interferon, gamma
Click here to display 55 evidence detail records.
HumanHLA-DQB13119
Click here to display 55 evidence detail records.
HumanEZH12145enhancer of zeste homolog 1 (Drosophila)
Click here to display 55 evidence detail records.
HumanCD40LG959CD40 ligand
Click here to display 55 evidence detail records.
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
Click here to display 55 evidence detail records.
HumanCD86942CD86 molecule
Click here to display 55 evidence detail records.
HumanBTK695Bruton agammaglobulinemia tyrosine kinase
Click here to display 55 evidence detail records.
HumanCXCR5643chemokine (C-X-C motif) receptor 5
Click here to display 55 evidence detail records.
HumanBCL6604B-cell CLL/lymphoma 6
Click here to display 55 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008474absent spleen germinal center0self