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Details
Link-It Detail - Jax Mouse Phenotype - increased cellular sensitivity to oxidative stress
Debug Stats
  • ### Total Build Time: 104 ms 20.516 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 428 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=1 ms Completed: 1 ms rowSize= 370 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 207 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 598 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 608 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.583 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=78 ms Completed: 78 ms rowSize= 15.441 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.188 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased cellular sensitivity to oxidative stress MP:0008412
Definition (1)
greater incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis
Synonyms (1)
"decreased cellular resistance to oxidative stress" EXACT
Parents (1)
img increased sensitivity to induced cell death MP:0008943
Children (1)
img increased cellular sensitivity to hydrogen peroxide MP:0008406
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img increased sensitivity to induced cell death MP:0008943
Genes (32)

Species:
human : 32
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanVASN114990vasorin
INFERRED
HumanSESN283667sestrin 2
INFERRED
HumanMAPKAP179109mitogen-activated protein kinase associated protein 1
INFERRED
HumanCC2D1A54862coiled-coil and C2 domain containing 1A
INFERRED
HumanSIRT751547sirtuin 7
INFERRED
HumanATMIN23300ATM interactor
INFERRED
HumanCCS9973copper chaperone for superoxide dismutase
Click here to display 26 evidence detail records.
HumanMTFR19650mitochondrial fission regulator 1
Click here to display 26 evidence detail records.
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
INFERRED
HumanRGN9104regucalcin
Click here to display 26 evidence detail records.
HumanSTC28614stanniocalcin 2
INFERRED
HumanWRN7486Werner syndrome, RecQ helicase-like
Click here to display 26 evidence detail records.
HumanUNG7374uracil-DNA glycosylase
Click here to display 26 evidence detail records.
HumanPRDX27001peroxiredoxin 2
Click here to display 26 evidence detail records.
HumanSLC1A36507solute carrier family 1 (glial high affinity glutamate transporter), member 3
INFERRED
HumanSLC1A16505solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
INFERRED
HumanRIT16016Ras-like without CAAX 1
INFERRED
HumanREG1B5968regenerating islet-derived 1 beta
Click here to display 26 evidence detail records.
HumanPRDX15052peroxiredoxin 1
Click here to display 26 evidence detail records.
HumanPAFAH25051platelet-activating factor acetylhydrolase 2, 40kDa
Click here to display 26 evidence detail records.
HumanNFE2L24780nuclear factor, erythroid 2-like 2
Click here to display 26 evidence detail records.
HumanGPX72882glutathione peroxidase 7
Click here to display 26 evidence detail records.
HumanGPX12876glutathione peroxidase 1
INFERRED
HumanGLRX2745glutaredoxin (thioltransferase)
Click here to display 26 evidence detail records.
HumanGCLM2730glutamate-cysteine ligase, modifier subunit
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008412increased cellular sensitivity to oxidative stress0self