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Details
Link-It Detail - Jax Mouse Phenotype - abnormal osteoclast differentiation
Debug Stats
  • ### Total Build Time: 266 ms 33.503 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 317 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 196 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.482 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=15 ms Completed: 15 ms rowSize= 12.314 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=241 ms Completed: 241 ms rowSize= 17.491 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal osteoclast differentiation MP:0008396
Definition (1)
atypical production of or inability to produce the specialized phagocytic cells associated with the absorption and removal of the mineralized matrix of bone tissue
Synonyms (1)
"abnormal chondrocyte differentiation" RELATED
Parents (3)
img abnormal skeleton development MP:0002113
img abnormal osteoclast morphology MP:0004982
img abnormal cell differentiation MP:0005076
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img skeleton phenotype MP:00053905img abnormal skeleton development MP:0002113
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img skeleton phenotype MP:00053906img abnormal osteoclast morphology MP:0004982
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal cell differentiation MP:0005076
Genes (75)

Species:
human : 75
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 108 evidence detail records.
HumanSIGLEC15284266sialic acid binding Ig-like lectin 15
Click here to display 108 evidence detail records.
HumanATP6V0D2245972ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
Click here to display 108 evidence detail records.
HumanTMEM64169200transmembrane protein 64
Click here to display 108 evidence detail records.
HumanPPARGC1B133522peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Click here to display 108 evidence detail records.
HumanOSCAR126014osteoclast associated, immunoglobulin-like receptor
Click here to display 108 evidence detail records.
HumanJDP2122953Jun dimerization protein 2
Click here to display 108 evidence detail records.
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 108 evidence detail records.
HumanDCSTAMP81501dendrocyte expressed seven transmembrane protein
Click here to display 108 evidence detail records.
HumanANKH56172ANKH inorganic pyrophosphate transport regulator
Click here to display 108 evidence detail records.
HumanIL17RB55540interleukin 17 receptor B
Click here to display 108 evidence detail records.
HumanFBLIM154751filamin binding LIM protein 1
Click here to display 108 evidence detail records.
HumanIL20RA53832interleukin 20 receptor, alpha
Click here to display 108 evidence detail records.
HumanCLDN1851208claudin 18
Click here to display 108 evidence detail records.
HumanCLEC2D29121C-type lectin domain family 2, member D
Click here to display 108 evidence detail records.
HumanDKK227123dickkopf WNT signaling pathway inhibitor 2
Click here to display 108 evidence detail records.
HumanHCST10870hematopoietic cell signal transducer
Click here to display 108 evidence detail records.
HumanTOB210766transducer of ERBB2, 2
Click here to display 108 evidence detail records.
HumanGAB29846GRB2-associated binding protein 2
Click here to display 108 evidence detail records.
HumanRASSF29770Ras association (RalGDS/AF-6) domain family member 2
Click here to display 108 evidence detail records.
HumanGPR559290G protein-coupled receptor 55
Click here to display 108 evidence detail records.
HumanSQSTM18878sequestosome 1
Click here to display 108 evidence detail records.
HumanINPP4B8821inositol polyphosphate-4-phosphatase, type II, 105kDa
Click here to display 108 evidence detail records.
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Click here to display 108 evidence detail records.
HumanGPR688111G protein-coupled receptor 68
Click here to display 108 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008396abnormal osteoclast differentiation0self