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Details
Link-It Detail - Jax Mouse Phenotype - abnormal B cell activation
Debug Stats
  • ### Total Build Time: 277 ms 31.689 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=263 ms Completed: 263 ms rowSize= 15.713 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.164 KB
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Jax Mouse Phenotype (1)
abnormal B cell activation MP:0008217
Definition (1)
any anomaly in the normal change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific
Parents (2)
img abnormal B cell differentiation MP:0002144
img abnormal B cell physiology MP:0002459
Children (1)
img abnormal B cell proliferation MP:0005153
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal B cell physiology MP:0002459
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal B cell physiology MP:0002459
Genes (153)

Species:
human : 153
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
INFERRED
HumanPIM3415116pim-3 oncogene
INFERRED
HumanTAB3257397TGF-beta activated kinase 1/MAP3K7 binding protein 3
INFERRED
HumanGAPT202309GRB2-binding adaptor protein, transmembrane
INFERRED
HumanBTLA151888B and T lymphocyte associated
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 70 evidence detail records.
HumanGABPB2126626GA binding protein transcription factor, beta subunit 2
INFERRED
HumanPIK3AP1118788phosphoinositide-3-kinase adaptor protein 1
INFERRED
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
INFERRED
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
INFERRED
HumanSPPL2A84888signal peptide peptidase like 2A
INFERRED
HumanORAI184876ORAI calcium release-activated calcium modulator 1
Click here to display 70 evidence detail records.
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanRASSF583593Ras association (RalGDS/AF-6) domain family member 5
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
Click here to display 70 evidence detail records.
HumanDCLRE1C64421DNA cross-link repair 1C
INFERRED
HumanSAMSN164092SAM domain, SH3 domain and nuclear localization signals 1
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanOTUD7B56957OTU domain containing 7B
INFERRED
HumanBANK155024B-cell scaffold protein with ankyrin repeats 1
INFERRED
HumanPPP2R3C55012protein phosphatase 2, regulatory subunit B'', gamma
Click here to display 70 evidence detail records.
HumanSIAE54414sialic acid acetylesterase
Click here to display 70 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008217abnormal B cell activation0self