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Details
Link-It Detail - Jax Mouse Phenotype - absent marginal zone B cells
Debug Stats
  • ### Total Build Time: 76 ms 31.007 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 384 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 366 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 173 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.025 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 19.072 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=48 ms Completed: 48 ms rowSize= 8.689 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
absent marginal zone B cells MP:0008183
Definition (1)
absence of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL
Synonyms (1)
"absent MZB cell" EXACT
Parents (2)
img absent mature B cells MP:0008212
img decreased marginal zone B cell number MP:0008182
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img decreased marginal zone B cell number MP:0008182
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img decreased marginal zone B cell number MP:0008182
Genes (14)

Species:
human : 14
SpeciesGeneGeneIdGene NameEvidence
HumanNKX2-3159296
Click here to display 18 evidence detail records.
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
Click here to display 18 evidence detail records.
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
Click here to display 18 evidence detail records.
HumanDLL128514delta-like 1 (Drosophila)
Click here to display 18 evidence detail records.
HumanTRAF27186TNF receptor-associated factor 2
Click here to display 18 evidence detail records.
HumanZEB16935zinc finger E-box binding homeobox 1
Click here to display 18 evidence detail records.
HumanSRF6722serum response factor (c-fos serum response element-binding transcription factor)
Click here to display 18 evidence detail records.
HumanLTBR4055lymphotoxin beta receptor (TNFR superfamily, member 3)
Click here to display 18 evidence detail records.
HumanLTA4049lymphotoxin alpha
Click here to display 18 evidence detail records.
HumanIRF53663interferon regulatory factor 5
Click here to display 18 evidence detail records.
HumanINPP5D3635inositol polyphosphate-5-phosphatase, 145kDa
Click here to display 18 evidence detail records.
HumanFOXO12308forkhead box O1
Click here to display 18 evidence detail records.
HumanCD19930CD19 molecule
Click here to display 18 evidence detail records.
HumanADAM10102ADAM metallopeptidase domain 10
Click here to display 18 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008183absent marginal zone B cells0self