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Details
Link-It Detail - Jax Mouse Phenotype - decreased marginal zone B cell number
Debug Stats
  • ### Total Build Time: 232 ms 37.303 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 402 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 373 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 193 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.037 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 585 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 16.437 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=221 ms Completed: 221 ms rowSize= 16.993 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.175 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
decreased marginal zone B cell number MP:0008182
Definition (1)
reduced number of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL
Synonyms (1)
"reduced marginal zone B cell number" EXACT
Parents (2)
img abnormal marginal zone B cell morphology MP:0008180
img decreased mature B cell number MP:0008211
Children (1)
img absent marginal zone B cells MP:0008183
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal marginal zone B cell morphology MP:0008180
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased mature B cell number MP:0008211
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased mature B cell number MP:0008211
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased mature B cell number MP:0008211
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased mature B cell number MP:0008211
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased mature B cell number MP:0008211
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img decreased mature B cell number MP:0008211
Genes (70)

Species:
human : 70
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1170575GTPase, IMAP family member 1
Click here to display 117 evidence detail records.
HumanNKX2-3159296
INFERRED
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
Click here to display 117 evidence detail records.
HumanSPPL2A84888signal peptide peptidase like 2A
Click here to display 117 evidence detail records.
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanDOCK881704dedicator of cytokinesis 8
Click here to display 117 evidence detail records.
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
Click here to display 117 evidence detail records.
HumanACKR357007atypical chemokine receptor 3
Click here to display 117 evidence detail records.
HumanPCID255795PCI domain containing 2
Click here to display 117 evidence detail records.
HumanSASH354440SAM and SH3 domain containing 3
Click here to display 117 evidence detail records.
HumanSIAE54414sialic acid acetylesterase
Click here to display 117 evidence detail records.
HumanTLR851311toll-like receptor 8
Click here to display 117 evidence detail records.
HumanTLR751284toll-like receptor 7
Click here to display 117 evidence detail records.
HumanBLNK29760B-cell linker
Click here to display 117 evidence detail records.
HumanDLL128514delta-like 1 (Drosophila)
INFERRED
HumanSPEN23013spen homolog, transcriptional regulator (Drosophila)
Click here to display 117 evidence detail records.
HumanIKZF322806IKAROS family zinc finger 3 (Aiolos)
Click here to display 117 evidence detail records.
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
Click here to display 117 evidence detail records.
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
Click here to display 117 evidence detail records.
HumanHAX110456HCLS1 associated protein X-1
Click here to display 117 evidence detail records.
HumanSH2D3C10044SH2 domain containing 3C
Click here to display 117 evidence detail records.
HumanGIT29815G protein-coupled receptor kinase interacting ArfGAP 2
Click here to display 117 evidence detail records.
HumanMAML19794mastermind-like 1 (Drosophila)
Click here to display 117 evidence detail records.
HumanFAIM39214Fas apoptotic inhibitory molecule 3
Click here to display 117 evidence detail records.
HumanARHGEF19138Rho guanine nucleotide exchange factor (GEF) 1
Click here to display 117 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008182decreased marginal zone B cell number0self