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Details
Link-It Detail - Jax Mouse Phenotype - abnormal marginal zone B cell morphology
Debug Stats
  • ### Total Build Time: 33 ms 27.231 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 382 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 175 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.040 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.043 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 8.336 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 14.548 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal marginal zone B cell morphology MP:0008180
Definition (1)
any structural anomaly of a CD23-negative, CD21-positive B cell of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL
Synonyms (1)
"abnormal MZB cell" EXACT
Parents (2)
img abnormal mature B cell morphology MP:0008171
img abnormal spleen marginal zone morphology MP:0002362
Children (2)
img decreased marginal zone B cell number MP:0008182
img increased marginal zone B cell number MP:0008181
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal spleen marginal zone morphology MP:0002362
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053977img abnormal spleen marginal zone morphology MP:0002362
Genes (96)

Species:
human : 96
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanATP11C286410ATPase, class VI, type 11C
INFERRED
HumanGAPT202309GRB2-binding adaptor protein, transmembrane
INFERRED
HumanGIMAP1170575GTPase, IMAP family member 1
INFERRED
HumanNKX2-3159296
Click here to display 10 evidence detail records.
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
INFERRED
HumanSPPL2A84888signal peptide peptidase like 2A
INFERRED
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanDOCK881704dedicator of cytokinesis 8
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanACKR357007atypical chemokine receptor 3
INFERRED
HumanPCID255795PCI domain containing 2
INFERRED
HumanSASH354440SAM and SH3 domain containing 3
INFERRED
HumanSIAE54414sialic acid acetylesterase
INFERRED
HumanTLR851311toll-like receptor 8
INFERRED
HumanTLR751284toll-like receptor 7
INFERRED
HumanBLNK29760B-cell linker
INFERRED
HumanDLL128514delta-like 1 (Drosophila)
INFERRED
HumanTNFRSF13B23495tumor necrosis factor receptor superfamily, member 13B
INFERRED
HumanSPEN23013spen homolog, transcriptional regulator (Drosophila)
INFERRED
HumanIKZF322806IKAROS family zinc finger 3 (Aiolos)
INFERRED
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
INFERRED
HumanTRAF3IP210758TRAF3 interacting protein 2
INFERRED
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
INFERRED
HumanHAX110456HCLS1 associated protein X-1
INFERRED
HumanSH2D3C10044SH2 domain containing 3C
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008180abnormal marginal zone B cell morphology0self