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Details
Link-It Detail - Jax Mouse Phenotype - absent Langerhans cell
Debug Stats
  • ### Total Build Time: 75 ms 80.171 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 372 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 556 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 587 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=34 ms Completed: 34 ms rowSize= 12.366 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 65.013 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
absent Langerhans cell MP:0008118
Definition (1)
absence of stellate dendritic cells of myeloid origin, that appear clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus
Parents (1)
img decreased Langerhans cell number MP:0008119
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img decreased Langerhans cell number MP:0008119
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img decreased Langerhans cell number MP:0008119
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanIL34146433interleukin 34
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
HumanCD20750489CD207 molecule, langerin
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
HumanTGFB17040transforming growth factor, beta 1
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
HumanITGB63694integrin, beta 6
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
HumanCSF1R1436colony stimulating factor 1 receptor
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
HumanCSF11435colony stimulating factor 1 (macrophage)
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
HumanRUNX3864runt-related transcription factor 3
img Jax MP, Pubmed Id: 14765120, MOUSE PHENOTYPE ID: MGI:102672
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:96615
img Jax MP, Pubmed Id: 17353357, MOUSE PHENOTYPE ID: MGI:98725
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 22729249, MOUSE PHENOTYPE ID: MGI:1923777
img Jax MP, Pubmed Id: 16356859, MOUSE PHENOTYPE ID: MGI:3762030
img Jax MP, Pubmed Id: 15897263, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 19022904, MOUSE PHENOTYPE ID: MGI:98725
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008118absent Langerhans cell0self