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Details
Link-It Detail - Jax Mouse Phenotype - abnormal T-helper 2 cell differentiation
Debug Stats
  • ### Total Build Time: 43 ms 29.118 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 349 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 191 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 16.513 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=41 ms Completed: 41 ms rowSize= 9.304 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.178 KB
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Jax Mouse Phenotype (1)
abnormal T-helper 2 cell differentiation MP:0008092
Definition (1)
atypical production of or inability to produce the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms (1)
"abnormal Th2 cell differentiation" EXACT
Parents (2)
img abnormal CD4-positive T cell differentiation MP:0008076
img abnormal T-helper 2 cell morphology MP:0002434
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img cellular phenotype MP:00053849img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal T-helper 2 cell morphology MP:0002434
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img abnormal T-helper 2 cell morphology MP:0002434
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img abnormal T-helper 2 cell morphology MP:0002434
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanRSAD291543radical S-adenosyl methionine domain containing 2
Click here to display 22 evidence detail records.
HumanTSLP85480thymic stromal lymphopoietin
Click here to display 22 evidence detail records.
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 22 evidence detail records.
HumanBHLHE4179365basic helix-loop-helix family, member e41
Click here to display 22 evidence detail records.
HumanIL17RA23765interleukin 17 receptor A
Click here to display 22 evidence detail records.
HumanICOSLG23308inducible T-cell co-stimulator ligand
Click here to display 22 evidence detail records.
HumanBATF10538basic leucine zipper transcription factor, ATF-like
Click here to display 22 evidence detail records.
HumanMAP4K38491mitogen-activated protein kinase kinase kinase kinase 3
Click here to display 22 evidence detail records.
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
Click here to display 22 evidence detail records.
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
Click here to display 22 evidence detail records.
HumanIL133596interleukin 13
Click here to display 22 evidence detail records.
HumanIL103586interleukin 10
Click here to display 22 evidence detail records.
HumanIL43565interleukin 4
Click here to display 22 evidence detail records.
HumanCBLB868Cbl proto-oncogene B, E3 ubiquitin protein ligase
Click here to display 22 evidence detail records.
HumanC3AR1719complement component 3a receptor 1
Click here to display 22 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008092abnormal T-helper 2 cell differentiation0self