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Details
Link-It Detail - Jax Mouse Phenotype - abnormal T-helper 1 cell differentiation
Debug Stats
  • ### Total Build Time: 80 ms 34.948 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=77 ms Completed: 77 ms rowSize= 15.143 KB
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Jax Mouse Phenotype (1)
abnormal T-helper 1 cell differentiation MP:0008088
Definition (1)
atypical production of or inability to produce the subset of the type of T-helper cell whose cytokine production favors cellular immune responses and delayed type hypersensitivity
Synonyms (1)
"abnormal T helper 1 cell differentiation" EXACT
Parents (2)
img abnormal T-helper 1 cell morphology MP:0002433
img abnormal CD4-positive T cell differentiation MP:0008076
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal T-helper 1 cell morphology MP:0002433
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img abnormal T-helper 1 cell morphology MP:0002433
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img abnormal T-helper 1 cell morphology MP:0002433
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img cellular phenotype MP:00053849img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal CD4-positive T cell differentiation MP:0008076
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal CD4-positive T cell differentiation MP:0008076
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
Click here to display 34 evidence detail records.
HumanSEMA4A64218sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
Click here to display 34 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 34 evidence detail records.
HumanCD27429126CD274 molecule
Click here to display 34 evidence detail records.
HumanSIT127240signaling threshold regulating transmembrane adaptor 1
Click here to display 34 evidence detail records.
HumanGADD45G10912growth arrest and DNA-damage-inducible, gamma
Click here to display 34 evidence detail records.
HumanMAP4K38491mitogen-activated protein kinase kinase kinase kinase 3
Click here to display 34 evidence detail records.
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
Click here to display 34 evidence detail records.
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
Click here to display 34 evidence detail records.
HumanREL5966v-rel avian reticuloendotheliosis viral oncogene homolog
Click here to display 34 evidence detail records.
HumanPTGER15731prostaglandin E receptor 1 (subtype EP1), 42kDa
Click here to display 34 evidence detail records.
HumanMAPK95601mitogen-activated protein kinase 9
Click here to display 34 evidence detail records.
HumanMAPK85599mitogen-activated protein kinase 8
Click here to display 34 evidence detail records.
HumanPRKCQ5588protein kinase C, theta
Click here to display 34 evidence detail records.
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
Click here to display 34 evidence detail records.
HumanGADD45B4616growth arrest and DNA-damage-inducible, beta
Click here to display 34 evidence detail records.
HumanMYD884615myeloid differentiation primary response 88
Click here to display 34 evidence detail records.
HumanSMAD74092SMAD family member 7
Click here to display 34 evidence detail records.
HumanIRF43662interferon regulatory factor 4
Click here to display 34 evidence detail records.
HumanIL103586interleukin 10
Click here to display 34 evidence detail records.
HumanIL43565interleukin 4
Click here to display 34 evidence detail records.
HumanIL23558interleukin 2
Click here to display 34 evidence detail records.
HumanIFNGR23460interferon gamma receptor 2 (interferon gamma transducer 1)
Click here to display 34 evidence detail records.
HumanEFNB11947ephrin-B1
Click here to display 34 evidence detail records.
HumanCD247919CD247 molecule
Click here to display 34 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008088abnormal T-helper 1 cell differentiation0self