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Details
Link-It Detail - Jax Mouse Phenotype - decreased CD4-positive T cell number
Debug Stats
  • ### Total Build Time: 5,069 ms 40.070 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 400 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 325 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 186 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.041 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 2.913 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 16.467 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=5,057 ms Completed: 5.057 Seconds rowSize= 17.441 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.174 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
decreased CD4-positive T cell number MP:0008075
Definition (1)
reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production
Synonyms (1)
"decreased CD4+ T cell number" EXACT
Parents (2)
img abnormal CD4-positive T cell number MP:0008073
img decreased single-positive T cell number MP:0008083
Children (6)
img absent CD4-positive T cells MP:0003790
img decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number MP:0010169
img decreased T-helper 17 cell number MP:0010220
img decreased T helper 1 cell number MP:0008087
img decreased T follicular helper cell number MP:0010187
img decreased T-helper 2 cell number MP:0008091
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal CD4-positive T cell number MP:0008073
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased single-positive T cell number MP:0008083
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased single-positive T cell number MP:0008083
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased single-positive T cell number MP:0008083
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased single-positive T cell number MP:0008083
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased single-positive T cell number MP:0008083
Genes (183)

Species:
human : 183
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
Click here to display 422 evidence detail records.
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 422 evidence detail records.
HumanTHEMIS387357thymocyte selection associated
Click here to display 422 evidence detail records.
HumanASXL1171023additional sex combs like 1 (Drosophila)
Click here to display 422 evidence detail records.
HumanGIMAP1170575GTPase, IMAP family member 1
Click here to display 422 evidence detail records.
HumanNKX2-3159296
Click here to display 422 evidence detail records.
HumanSPNS2124976spinster homolog 2 (Drosophila)
Click here to display 422 evidence detail records.
HumanMSI2124540musashi RNA-binding protein 2
Click here to display 422 evidence detail records.
HumanHNRNPLL92906heterogeneous nuclear ribonucleoprotein L-like
Click here to display 422 evidence detail records.
HumanBMF90427Bcl2 modifying factor
Click here to display 422 evidence detail records.
HumanNFATC2IP84901nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
INFERRED
HumanSPPL2A84888signal peptide peptidase like 2A
Click here to display 422 evidence detail records.
HumanSHARPIN81858SHANK-associated RH domain interactor
Click here to display 422 evidence detail records.
HumanDOCK881704dedicator of cytokinesis 8
Click here to display 422 evidence detail records.
HumanNKAP79576NFKB activating protein
Click here to display 422 evidence detail records.
HumanBCL11B64919B-cell CLL/lymphoma 11B (zinc finger protein)
Click here to display 422 evidence detail records.
HumanATG364422autophagy related 3
Click here to display 422 evidence detail records.
HumanDCLRE1C64421DNA cross-link repair 1C
Click here to display 422 evidence detail records.
HumanIL2159067interleukin 21
Click here to display 422 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
Click here to display 422 evidence detail records.
HumanDLL454567delta-like 4 (Drosophila)
INFERRED
HumanBCL11A53335B-cell CLL/lymphoma 11A (zinc finger protein)
INFERRED
HumanGMNN51053geminin, DNA replication inhibitor
Click here to display 422 evidence detail records.
HumanFOXP350943forkhead box P3
INFERRED
HumanIL21R50615interleukin 21 receptor
Click here to display 422 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008075decreased CD4-positive T cell number0self