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Details
Link-It Detail - Jax Mouse Phenotype - absent B cells
Debug Stats
  • ### Total Build Time: 120 ms 32.993 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 356 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 443 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1.008 KB
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1.014 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=22 ms Completed: 22 ms rowSize= 13.600 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=66 ms Completed: 66 ms rowSize= 15.295 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
absent B cells MP:0008071
Definition (1)
absence of lymphocytes that expresses membrane-bound antibody, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens
Parents (2)
img absent lymphocyte MP:0000726
img decreased B cell number MP:0005017
Children (2)
img absent immature B cells MP:0008213
img absent mature B cells MP:0008212
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased B cell number MP:0005017
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img decreased B cell number MP:0005017
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img decreased B cell number MP:0005017
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased B cell number MP:0005017
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased B cell number MP:0005017
Genes (57)

Species:
human : 57
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SpeciesGeneGeneIdGene NameEvidence
HumanATP11C286410ATPase, class VI, type 11C
INFERRED
HumanNKX2-3159296
INFERRED
HumanPIK3AP1118788phosphoinositide-3-kinase adaptor protein 1
INFERRED
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
INFERRED
HumanNLRP3114548NLR family, pyrin domain containing 3
Click here to display 39 evidence detail records.
HumanFNIP196459folliculin interacting protein 1
Click here to display 39 evidence detail records.
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanDCLRE1C64421DNA cross-link repair 1C
Click here to display 39 evidence detail records.
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
INFERRED
HumanAICDA57379activation-induced cytidine deaminase
INFERRED
HumanGON4L54856gon-4-like (C. elegans)
Click here to display 39 evidence detail records.
HumanBCL11A53335B-cell CLL/lymphoma 11A (zinc finger protein)
Click here to display 39 evidence detail records.
HumanBLNK29760B-cell linker
INFERRED
HumanDLL128514delta-like 1 (Drosophila)
INFERRED
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
INFERRED
HumanBATF10538basic leucine zipper transcription factor, ATF-like
INFERRED
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
Click here to display 39 evidence detail records.
HumanFOXN18456forkhead box N1
Click here to display 39 evidence detail records.
HumanTRAF27186TNF receptor-associated factor 2
INFERRED
HumanTNF7124tumor necrosis factor
INFERRED
HumanZEB16935zinc finger E-box binding homeobox 1
INFERRED
HumanTCF36929transcription factor 3
Click here to display 39 evidence detail records.
HumanSYK6850spleen tyrosine kinase
INFERRED
HumanSRF6722serum response factor (c-fos serum response element-binding transcription factor)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008071absent B cells0self