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Details
Link-It Detail - Jax Mouse Phenotype - abnormal podocyte slit diaphragm morphology
Debug Stats
  • ### Total Build Time: 28 ms 23.853 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 380 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 597 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 587 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.595 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 19.001 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal podocyte slit diaphragm morphology MP:0008060
Definition (1)
any structural anomaly of the thin membrane that covers the podocyte filtration slit which allows small molecules such as water, glucose, and ionic salts to pass through while retaining larger macromolecules in the bloodstream
Parents (1)
img abnormal podocyte slit junction morphology MP:0008062
Children (1)
img absent podocyte slit diaphragm MP:0008061
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:000536711img abnormal podocyte slit junction morphology MP:0008062
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
INFERRED
HumanVEGFA7422vascular endothelial growth factor A
img Jax MP, Pubmed Id: 20484117, MOUSE PHENOTYPE ID: MGI:96217
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 19279126, MOUSE PHENOTYPE ID: MGI:2450360
img Jax MP, Pubmed Id: 15200417, MOUSE PHENOTYPE ID: MGI:99216
img Jax MP, Pubmed Id: 16611717
img Jax MP, Pubmed Id: 16837631
img Jax MP, Pubmed Id: 19142224, MOUSE PHENOTYPE ID: MGI:3762408
HumanPODXL5420podocalyxin-like
INFERRED
HumanNPHS14868nephrosis 1, congenital, Finnish type (nephrin)
INFERRED
HumanLMX1B4010LIM homeobox transcription factor 1, beta
INFERRED
HumanHPRT13251hypoxanthine phosphoribosyltransferase 1
img Jax MP, Pubmed Id: 16837631
img Jax MP, Pubmed Id: 19279126, MOUSE PHENOTYPE ID: MGI:2450360
img Jax MP, Pubmed Id: 15200417, MOUSE PHENOTYPE ID: MGI:99216
img Jax MP, Pubmed Id: 16611717
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 19142224, MOUSE PHENOTYPE ID: MGI:3762408
img Jax MP, Pubmed Id: 20484117, MOUSE PHENOTYPE ID: MGI:96217
HumanFOXC22303forkhead box C2 (MFH-1, mesenchyme forkhead 1)
INFERRED
HumanCD151977CD151 molecule (Raph blood group)
INFERRED
HumanDDR1780discoidin domain receptor tyrosine kinase 1
img Jax MP, Pubmed Id: 16837631
img Jax MP, Pubmed Id: 15200417, MOUSE PHENOTYPE ID: MGI:99216
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 19142224, MOUSE PHENOTYPE ID: MGI:3762408
img Jax MP, Pubmed Id: 19279126, MOUSE PHENOTYPE ID: MGI:2450360
img Jax MP, Pubmed Id: 16611717
img Jax MP, Pubmed Id: 20484117, MOUSE PHENOTYPE ID: MGI:96217
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008060abnormal podocyte slit diaphragm morphology0self