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Details
Link-It Detail - Jax Mouse Phenotype - abnormal retinal ganglion cell morphology
Debug Stats
  • ### Total Build Time: 77 ms 24.904 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 410 bytes
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  • CONCEPT_GENES gt=71 ms Completed: 71 ms rowSize= 15.820 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal retinal ganglion cell morphology MP:0008056
Definition (1)
any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain
Parents (2)
img abnormal sensory neuron morphology MP:0000965
img abnormal retinal ganglion layer morphology MP:0005241
Children (3)
img decreased retinal ganglion cell number MP:0006309
img increased retinal ganglion cell number MP:0002983
img retinal ganglion cell degeneration MP:0008067
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal sensory neuron morphology MP:0000965
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img abnormal sensory neuron morphology MP:0000965
img mammalian phenotype MP:0000001img vision/eye phenotype MP:000539110img abnormal retinal ganglion layer morphology MP:0005241
Genes (65)

Species:
human : 65
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPRSS56646960protease, serine, 56
INFERRED
HumanBARHL2343472BarH-like homeobox 2
INFERRED
HumanPTF1A256297pancreas specific transcription factor, 1a
INFERRED
HumanATOH7220202atonal homolog 7 (Drosophila)
Click here to display 56 evidence detail records.
HumanFOXN4121643forkhead box N4
Click here to display 56 evidence detail records.
HumanOPN494233opsin 4
Click here to display 56 evidence detail records.
HumanPLXNA491584plexin A4
Click here to display 56 evidence detail records.
HumanOPA380207optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
INFERRED
HumanHPS679803Hermansky-Pudlak syndrome 6
Click here to display 56 evidence detail records.
HumanMPP564398membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
INFERRED
HumanSMOC164093SPARC related modular calcium binding 1
INFERRED
HumanNTN459277netrin 4
Click here to display 56 evidence detail records.
HumanNEUROD458158neuronal differentiation 4
INFERRED
HumanSEMA6A57556sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Click here to display 56 evidence detail records.
HumanDSCAML157453Down syndrome cell adhesion molecule like 1
Click here to display 56 evidence detail records.
HumanPOMGNT155624protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
INFERRED
HumanPLXNA355558plexin A3
Click here to display 56 evidence detail records.
HumanLGR455366leucine-rich repeat containing G protein-coupled receptor 4
INFERRED
HumanSEMA5B54437sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Click here to display 56 evidence detail records.
HumanVAX225806ventral anterior homeobox 2
Click here to display 56 evidence detail records.
HumanPANX124145pannexin 1
INFERRED
HumanTRIM223321tripartite motif containing 2
INFERRED
HumanGPNMB10457glycoprotein (transmembrane) nmb
INFERRED
HumanGDF1110220growth differentiation factor 11
INFERRED
HumanHS2ST19653heparan sulfate 2-O-sulfotransferase 1
Click here to display 56 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008056abnormal retinal ganglion cell morphology0self